Nexotojeong (Itopride Hydrochloride)

Adult dose

○ Adults: Administer 50 mg of itopride hydrochloride orally 3 times daily before meals. Reduce the dose appropriately according to symptoms.

This medication must not be administered to patients who have hypersensitivity to this drug or its components, or have a history of hypersensitivity. It should also not be used in patients for whom gastrointestinal stimulation may be harmful, such as those with gastrointestinal bleeding, mechanical obstruction, or perforation. This drug contains lactose, so it should not be used in individuals with hereditary issues like galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption. During the use of this drug, serious allergic reactions such as shock or anaphylaxis may occur, so if symptoms like hypotension, difficulty breathing, or hives appear, administration should be stopped immediately, and appropriate treatment should be sought. Liver function abnormalities or jaundice symptoms may occur, so liver-related evaluations should be conducted periodically, and if abnormalities are found, administration should be stopped. Gastrointestinal symptoms such as nausea, diarrhea, constipation, abdominal pain, and increased saliva may occur, as well as neurological symptoms like headache, anxiety, sleep disturbances, and dizziness. Gynecomastia or increased prolactin levels may occur, and if such symptoms appear, consultation with a physician is necessary to consider discontinuation. Blood-related issues such as thrombocytopenia or leukopenia may occur, and regular blood tests should be performed to monitor the condition, with discontinuation if abnormalities appear. Kidney function markers may increase, so kidney status should also be monitored periodically. Hypersensitivity reactions such as itching, rash, or redness may rarely occur; if such symptoms appear, administration should be stopped, and appropriate measures taken. There may also be symptoms of tremors or extrapyramidal symptoms, so if abnormal signs occur, consultation with healthcare professionals is required. This medication enhances the action of acetylcholine, so it should be used with consideration of this point, and long-term use is not recommended if gastrointestinal symptoms do not improve. When taken with anticholinergics, the effect of this medication may be reduced, so caution should be exercised and intervals between doses maintained. Pregnant women or those who may become pregnant should only use this medication when the benefits outweigh the risks, as its safety has not been established. During breastfeeding, this medication may be excreted in breast milk, so it should be avoided, and if absolutely necessary, breastfeeding should be discontinued. Safety in children has not been adequately established, so it should be used carefully. Elderly patients may experience adverse reactions more easily due to decreased physiological functions, so symptoms should be closely observed, and dosage adjustments or breaks considered if necessary. This medication should be kept out of reach of children, and transferring it to another container should be avoided to prevent accidents and degradation of quality.

• Shock
• anaphylactic-like symptoms
• decreased blood pressure
• difficulty breathing
• laryngeal edema
• urticaria
• pallor
• sweating
• liver dysfunction
• jaundice

This medication should be stored in a tightly closed container to protect it from air or moisture, and it is important to maintain a storage temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the drug's effectiveness and prevent degradation.

Appearance

White, round film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle