Lipistat 10 mg (Atorvastatin Calcium Hydrate)

Adult dose

The recommended initial dose of atorvastatin is 10 mg once daily, and if a larger reduction in LDL cholesterol levels is required, it can be started at 20 mg or 40 mg once daily. The dosage range is 10 to 80 mg once daily. The initial and maintenance doses should be individualized based on treatment goals and response, and lipid levels should be evaluated and dose adjustments made within 2 to 4 weeks.

Child dose

The recommended initial dose for pediatric patients (10-17 years) with heterozygous familial hypercholesterolemia is 10 mg once daily, with a recommended maximum dose of 20 mg once daily. The dosing can be adjusted appropriately based on treatment goals.

This medication may have adverse effects on muscles, so if there is severe muscle pain or weakness, or a significant increase in creatine kinase levels, treatment should be discontinued immediately. This medication may impact liver function, so it should not be administered to patients with liver disease or elevated liver enzyme levels. Women who are pregnant, may become pregnant, or are breastfeeding should not use this medication. Children under 10 years of age should not take this medication, and children aged 10 to 17 should use it cautiously under a doctor's guidance. Patients with a history of alcohol dependency or liver disease, and those with impaired kidney function should use this medication with special caution. There are many potential interactions with other medications, especially if taken with certain antibiotics, antifungals, or antivirals, as the risk of muscle damage may increase; therefore, consultation with a physician is necessary. If symptoms such as muscle pain, weakness, or fever occur while taking this medication, inform healthcare personnel immediately and have tests done. If symptoms of liver dysfunction (e.g., jaundice, nausea, vomiting, fatigue) occur, discontinue the medication immediately and consult a physician. Grapefruit juice may increase blood levels of this medication; therefore, be cautious not to consume it excessively. It is safe to have regular liver function tests and muscle-related tests while taking this medication. Store this medication out of reach of children and it is recommended to keep it in the original container. There is no specific antidote for overdose, so appropriate treatment should be administered according to symptoms, and liver function and muscle condition should be checked through blood tests.

Serious side effects

• Urticaria
• angioedema
• anaphylaxis
• erythema multiforme
• Stevens-Johnson syndrome
• toxic epidermal necrolysis
• acute liver failure
• non-alcoholic steatohepatitis
• hepatitis
• liver failure

Mild side effects

• Weakness
• fatigue
• chest pain
• peripheral edema
• tiredness
• fever
• pharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

Store this medication in a tightly closed container to prevent exposure to air or moisture, and maintain the storage temperature between 1°C and 30°C at room temperature. By storing it this way, the effectiveness of the medication can be preserved for a longer time.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle