Clarithromycin 250mg (Clarithromycin)

Adult dose

Adults: Clarithromycin is usually administered at 250mg (potency) per dose twice daily; for severe infections, administer 500mg (potency) per dose twice daily. The usual duration of treatment is 7～14 days. In patients with renal failure and creatinine clearance of 30mL/min or less, the dose should be reduced by half: 250mg (potency) once daily, or 250mg (potency) twice daily for severe infections. Do not administer for more than 14 days to these patients. Mycobacterial infections: Administer 500mg (potency) per dose twice daily. In this case, it should be administered concomitantly with other antimycobacterial agents such as ethambutol, clofazimine, and rifampin. Eradication of Helicobacter pylori in patients with duodenal ulcers: Administer 500mg (potency) of this medicine 3 times daily for 14 days concomitantly with omeprazole 40mg once daily, followed by omeprazole 40mg once daily for 14 consecutive days. That is, administer clarithromycin 500mg (potency) per dose 3 times daily for 14 days (days 1～14), and omeprazole 40mg once daily for 28 days (days 1～28).

Child dose

Children 12 years and older: Same as adults. For children under 12 years, use clarithromycin dry syrup.

This medication should not be used in certain patients. Patients allergic to this medication or similar antibiotics, those with specific heart conditions, or patients with severely impaired liver or kidney function should avoid taking it. In addition, it is advisable for pregnant or breastfeeding women not to use this medication. This medication should be used cautiously in patients with impaired liver or kidney function, those with heart disease, elderly patients, and those taking specific other medications. Special attention is required if taken concurrently with other antibiotics or medications that may affect the heart. While taking this medication, various side effects may occur, including allergic reactions, gastrointestinal disturbances, liver or kidney function abnormalities, skin rashes, and central nervous system symptoms. If any symptoms appear, immediate consultation with a doctor is necessary. As this medication interacts with many other drugs, it is important to inform the healthcare provider about any current medications being taken. Care should especially be taken when taken alongside heart-related medications, anticoagulants, certain antifungals, immunosuppressants, and antihyperglycemic agents. Pregnant or nursing individuals should not take this medication, and if necessary, breastfeeding should be discontinued. In the case of children or the elderly, consultation with healthcare professionals is also required before administration, particularly for elderly patients with impaired kidney function, as dose adjustments may be needed. Regular monitoring of liver and kidney function tests may be required while on this medication. In case of overdose, gastrointestinal disturbances or central nervous system symptoms may appear, and proper treatment should be obtained according to physician guidelines. This medication should not be refrigerated and should be stored at room temperature away from direct sunlight.

Shock, anaphylactic symptoms, dyspnea, convulsions, flushing, rash, itching, urticaria, skin flushing, angioedema, joint swelling, drug rash, abdominal bloating, nausea, vomiting, dyspepsia, abdominal pain, discomfort, gas retention, diarrhea, oral mucosal erosion, epigastric pain, thirst, transient tooth discoloration, pancreatitis, increased amylase, dysgeusia, anorexia, constipation, discoloration of stool, pseudomembranous colitis, hemorrhagic colitis, fever, cough, eosinophilia, eosinophilic pulmonary infiltrates, interstitial pneumonia, chronic bronchitis, exacerbation of acute maxillary sinusitis, eosinophilia, thrombocytopenia, pancytopenia, hemolytic anemia, leukopenia, agranulocytosis, dizziness, depression, loss of taste, loss of smell, anxiety, insomnia, nightmares, tinnitus, confusion, disorientation, hallucinations, psychosis, depersonalization, convulsions, tremors, numbness, behavioral changes, Stevens-Johnson syndrome, toxic epidermal necrolysis, allergic purpura, drug rash (DRESS), jaundice, hepatocellular hepatitis, cholestatic hepatitis, increased liver enzymes, liver dysfunction, liver failure, fulminant hepatitis, elevated AST, elevated ALT, elevated γ-GTP, elevated LDH, elevated ALP, increased total bilirubin, elevated serum creatinine, increased BUN, interstitial nephritis, renal failure, rhabdomyolysis, stomatitis, glossitis, oral candidiasis, QT prolongation, ventricular tachycardia, Torsades de pointes, lethargy, headache, taste distortion, hearing loss, paresthesia, arthralgia, myalgia, olfactory dysfunction, tinnitus, hearing impairment, hypoglycemia, purpuric rash, acute generalized exanthematous pustulosis, muscle spasms, musculoskeletal rigidity, myopathy, elevated blood urea, nephritis, phlebitis at injection site, pain at injection site, inflammation at injection site, fever, muscle weakness, chest pain, chills, fatigue, abnormal albumin-globulin ratio, increased serum alkaline phosphatase, elevated serum lactate dehydrogenase, increased international normalized ratio, prolonged prothrombin time, urine discoloration, cardiac arrest, atrial fibrillation, ECG QT prolongation, ectopic beats, palpitations, vasodilation, asthma, epistaxis, pulmonary embolism, esophagitis, gastroesophageal reflux disease, gastritis, rectal pain, belching, bloating, tongue discoloration, tooth discoloration, hyperhidrosis, papular rash, acne, Henoch-Schonlein purpura

This medication is sensitive to light and should be stored in a light-resistant container. It is also recommended to store it at a cool temperature between 15 degrees and 30 degrees Celsius. This way of storage helps to maintain the medication's effectiveness.

Appearance

Yellow oval film-coated tablets with a vanilla flavor

Package unit

30 tablets/bottle, 100 tablets/bottle