Rezolo 2mg (Prucalopride Succinate)

Adult dose

This medication is administered orally and can be taken at any time during the day regardless of meals. Adults should take 2mg once daily. Elderly patients aged 65 years and older should start with a dosage of 1mg once daily and may increase to 2mg once daily if necessary. For patients with severe renal impairment, 1mg should be given once daily; no dosage adjustment is needed for patients with mild to moderate renal impairment. For patients with severe liver impairment, a dosage of 1mg once daily is recommended.

This medication should not be administered to certain patients. For example, individuals allergic to the active ingredient or excipients of this medication, patients with severely impaired kidney function requiring dialysis, and patients with serious bowel issues may be at risk from using this medication. Moreover, patients with genetic issues such as lactose intolerance should also avoid this medication. In patients with severe renal impairment, the dosage of this medication should be reduced and administered cautiously. Patients with other serious conditions affecting the liver, heart, lungs, or nervous system should also be careful when using this medication. In particular, those with a history of arrhythmias or ischemic heart disease should use this medication with caution. Taking this medication may commonly cause gastrointestinal disturbances such as headaches, abdominal pain, nausea, and diarrhea. Most side effects are mild and often resolve naturally over time. Additionally, symptoms such as fatigue, dizziness, and palpitations may also occur, so if symptoms are severe, consult a physician. Severe diarrhea may reduce the effectiveness of oral contraceptives, so it is advisable to use additional contraceptive methods while taking this medication. Furthermore, symptoms of depression or suicidal thoughts may arise during the use of this medication, so any changes in mood or behavior should be promptly reported to healthcare professionals. When used with other medications, interactions are generally minimal; however, caution is necessary as drug concentrations may change when used with certain medications. In particular, when used with drugs that prolong the QT interval, one must take care as it may affect the heart. Use during pregnancy is not recommended, and women of childbearing age should ensure effective contraception during treatment. Use by breastfeeding women is also not recommended. It is advisable not to use this medication in children or adolescents under 18 years of age. In case of overdose, symptoms such as headaches, nausea, and diarrhea may occur, and treatment should be provided according to the symptoms. This medication may cause dizziness or fatigue on the first day of administration, so caution is needed when driving or operating machinery. Store this medication in a container that blocks light and air, and avoid storing it in a humid environment. The appropriate storage temperature is room temperature between 1 to 30 degrees Celsius.

Serious side effects

Chest tightness

Mild side effects

Headache, gastrointestinal symptoms (abdominal pain, nausea, diarrhea), dizziness, tremor, migraine, palpitations, light-headedness, vomiting, indigestion, rectal bleeding, bloating, abnormal bowel sounds, frequent urination, fatigue, fever, malaise, indigestion, abdominal distension, abdominal discomfort, gastroesophageal reflux disease, rectal pain, hemorrhoids, functional gastrointestinal disorders, loose stools, esophagitis, duodenal ulcer, nasopharyngitis, bronchitis, herpes zoster, athlete's foot, bacterial vaginosis, bacterial pneumonia.

This medication should be stored in a container that blocks light and air, and kept away from humid areas. The appropriate storage temperature is room temperature between 1 to 30 degrees Celsius.

Appearance

Pink, round film-coated tablet

Package unit

28 tablets (7 tablets * 4 PTP) / box