IRACODON 10 mg (Oxycodone Hydrochloride)

Adult dose

This medicine is administered to adults aged 18 years and older. For patients with chronic pain, rather than administering it only when pain occurs, administer the lowest dose at regular intervals (4～6 hours) that prevents recurrence of pain and provides adequate analgesia. Generally, the initial dose is 5 mg of oxycodone hydrochloride hydrate every 4～6 hours. Adjust the dose according to each patient's response to the initial dose and the severity of adverse reactions. When switching from a fixed-ratio opioid/non-opioid analgesic regimen to this medicine, determine whether to continue the non-opioid analgesic. If discontinuation of the non-opioid analgesic is decided, titrate the dose of this medicine in consideration of the level of analgesia and adverse reactions associated with the method of administration. If continuing the non-opioid analgesic as a separate single-ingredient product, set the initial dose of this medicine based on the most recent opioid dose as a baseline for subsequent dose increases. Adjust the dose according to each patient's response and the severity of adverse reactions. When switching from another opioid analgesic regimen to this medicine, determine the initial dose by calculating the potency and conversion ratio of the existing analgesic. 10 mg of this medicine is equivalent to 20 mg of oral morphine. After switching to this medicine, close monitoring of the patient and dose adjustment according to each patient's response and the severity of adverse reactions are essential. In particular, patients whose disease status changes rapidly may require additional analgesics for breakthrough pain or predictable pain during periods of activity, as well as an increase in the total daily dose of this medicine. In general, reduce the therapeutic dose by 25～50 % of the daily dose while carefully monitoring for signs and symptoms of withdrawal. If the patient develops signs or symptoms of withdrawal, increase the dose to the previous level and taper more slowly, for example by extending the interval between dose reductions or reducing the amount of each dose reduction.

Child dose

Do not administer to children and adolescents under 18 years of age.

This drug is a narcotic analgesic and should be taken with extreme caution when used in combination with other central nervous system depressants or alcohol, as it may cause severe drowsiness, respiratory distress, coma, and even death. It should not be administered to individuals with hypersensitivity to this drug or those with severe respiratory distress, asthma attacks, severe liver or kidney dysfunction, acute alcohol intoxication, heart failure, seizure disorders, hemorrhagic colitis, pregnant women, nursing mothers, or children under 18 years of age. For patients with heart disease, low blood pressure, shock, metabolic acidosis, hypothyroidism, adrenal insufficiency, elderly individuals, or debilitated patients, care should be taken while administering, and continued observation is needed due to the risk of drug abuse and dependence. Various side effects such as nausea, vomiting, constipation, drowsiness, dizziness, headache, itching, insomnia, and others may occur; if any unusual symptoms arise, consult a doctor. Avoid driving or operating hazardous machinery while taking this drug, and consider dietary adjustments or use of laxatives for constipation prevention after consultation with a physician. This drug should not be administered to pregnant or nursing mothers. If pregnant or possibly pregnant, it is crucial to inform the doctor. Patients with impaired liver or kidney function should have their dosage adjusted, and due to numerous drug interactions, always consult a doctor or pharmacist when taking this medication with other drugs. In case of overdose, severe symptoms like respiratory depression, decreased consciousness, and low blood pressure may occur, requiring immediate emergency treatment. The safety and efficacy of this drug in pediatric patients have not been established; therefore, it is not used in individuals under 18 years of age. Elderly patients, whose bodily functions may be weakened, should start at a low dose to avoid risks of respiratory depression and be administered with caution.

Yawning, sneezing, tearing, sweating, nausea, vomiting, diarrhea, abdominal pain, pupil dilation, headache, insomnia, anxiety, delusion, convulsions, tremors, pain in muscles and joints throughout the body, breathing difficulty, palpitations, difficulty breathing, slow breathing, irregular breathing, apnea, low blood pressure, shock, confusion, cardiovascular depression, heart attack, atelectasis, bronchospasm, laryngeal edema, paralytic ileus, toxic megacolon, anaphylactic reaction, nausea, constipation, vomiting, headache, itching, insomnia, dizziness, weakness, drowsiness, rash, hives, itching, allergic reaction, photosensitivity reaction, deep vein thrombosis, heart failure, bleeding, migraine, palpitations, tachycardia, arrhythmia, blood pressure fluctuations, hypotension, orthostatic hypotension, fainting, agitation, anxiety, emotional changes, restlessness, dry mouth, tension, sensory abnormalities, nerve irritability, neuralgia, personality disorder, tremors, vasodilation, strange dreams, nightmares, numbness, heavy feeling in the head, drowsiness, insomnia, dizziness, hallucinations, consciousness disturbance, muscle contraction, headache, visual accommodation disorder, miosis, convulsions, tremors, forgetfulness, feelings of euphoria, hypersensitivity to pain, loss of appetite, diarrhea, indigestion, dysphagia, gingivitis, glossitis, nausea, vomiting, thirst, gastric discomfort, abdominal pain, abdominal bloating, taste disorders, belching, hiccups, gastric inflammation, constipation, nausea, vomiting, edema, peripheral edema, back pain, cold, fever, influenza-like symptoms, infection, neck pain, sepsis, anemia, iron deficiency anemia, leukopenia, joint pain, arthritis, bone pain, myalgia, pathological fracture, bronchitis, increased coughing, dyspnea, nosebleed, laryngeal spasm, lung abnormalities, pharyngitis, rhinitis, sinusitis, central sleep apnea syndrome, shingles, exfoliative dermatitis, dry skin, urinary tract infection, dysuria, urine retention, dehydration, decreased libido, erectile dysfunction, amblyopia, weakness, fatigue, chest tightness, amenorrhea, gout, hyperglycemia, respiratory depression, coma, stupor, skeletal muscle relaxation, cold skin, miosis, bradycardia, hypotension, apnea, cardiovascular collapse, cardiac arrest

This medication is sensitive to light and must be stored in a tightly closed container that protects it from light. Also, it's important to maintain a storage temperature between 1 and 30 degrees Celsius to preserve the medication's effectiveness.

Appearance

White oblong tablets

Package unit

100 tablets (10 tablets/PTP x 10)