Greenplast Q Prefilled Syringe Kit

Adult use

Dosage is determined according to the area of the wound surface to be treated or the defect area to be filled. It is typically used according to the size of the surface area requiring adhesion. Up to 8 cm² use 2 mL kit Up to 16 cm² use 4 mL kit Usage 1) Thawing (1) Remove the drug from the freezer and allow it to sit at room temperature (30 - 50 minutes). However, for emergency surgeries, heat the syringe in a sterilized water bath below 37 °C. (2)

Since this drug is derived from human plasma, it cannot be guaranteed that there are no viruses or infectious agents that can be transmitted through blood. Therefore, it is recommended that patients with hemophilia or those with weakened immune systems receive vaccinations such as the hepatitis A vaccine, and that doctors regularly check for signs of infection. Additionally, it is crucial to provide patients with sufficient information about the risk of infection when using this drug and to use it minimally only when absolutely necessary. This drug should not be used in patients with severe bleeding, those allergic to the bovine protein contained in the drug, or in cases where it is injected directly into blood vessels. Patients with hemolytic anemia or severe anemia and those with weakened immune systems should use this medication with caution due to the potential risk of infection. In rare cases, individuals with a history of repeated use of this drug or who are allergic to bovine protein may experience allergic reactions such as shortness of breath, skin rash, and hypotension, and if symptoms occur, use should be discontinued immediately and treatment sought. Adverse reactions such as fever, vomiting, and headaches may occur due to the thrombin component in this medication. As it is difficult to fully remove viruses like Parvovirus B19, post-administration monitoring is essential, especially for pregnant women or those with weakened immune systems, as serious symptoms may arise. Care should be taken to prevent the drug from contacting areas other than the treatment site, and additional hemostatic measures must be taken in cases of severe bleeding. Caution is required during endoscopic procedures as local injection of this drug may cause tissue damage or hematoma and, rarely, pancreatitis. Iodine, hydrogen peroxide, and alcohol may reduce the efficacy of this drug, and interactions may occur due to calcium content when administered intravenously to patients taking cardiac glycosides. The safety of this drug during pregnancy is not firmly established, and it may affect the fetus, so it should only be used when deemed absolutely necessary. This drug is intended for local use only and should not be administered intravenously or mixed with other medications. It is best to use the drug immediately after thawing, store it at room temperature for no more than 72 hours, and ensure it is not refrozen. When stored, maintain a frozen state at below -20 degrees Celsius.

Serious side effects

Urticaria, dyspnea, anaphylactic reactions (including severe anaphylactic shock)

Mild side effects

• Fever
• vomiting
• headache
• flushing
• hypotension
• bronchospasm

This drug should be stored in a sealed container to protect it from exposure to air and should be kept frozen at temperatures below -20 degrees Celsius. This will help maintain the drug’s effectiveness and safety.

Appearance

A pair of prefilled syringes with a white to pale yellow freeze-dried solution inside, sealed at both ends.

Package unit

1 kit / box [kit (2 milliliters)], 1 kit / box [kit (4 milliliters)]