MediKinett Retard Capsule 10mg (Methylphenidate Hydrochloride)

Adult dose

The dose of this medicine should be individualized according to the patient's response and tolerability. This medicine should be administered with a meal or immediately after a meal. If a patient taking another formulation of methylphenidate hydrochloride is switched to this medicine, it must be administered immediately after a meal. Take this medicine, or its contents, intact with water. Do not chew or crush the contents of this medicine. Adults: Administer this medicine 2 times a day (morning and noon), immediately after meals. The initial dose is 5mg per dose, administered 2 times a day (morning and noon). Increase the daily dose by 10mg each week according to the patient's treatment response and tolerability. The maximum daily dose of this medicine is 1mg/kg and must not exceed 80mg a day. Adult patients who have been continuously taking this medicine since childhood or adolescence should continue taking the same dose they are currently taking. The safety and efficacy of this medicine for long-term administration for more than 6 months have not been studied. When prescribing this medicine long term to patients with ADHD, periodically reassess its efficacy for long-term use by temporarily interrupting drug treatment and conducting a trial to evaluate the patient's social functioning. If symptoms worsen or other adverse reactions occur, reduce the dose and, if necessary, discontinue this medicine. If symptoms do not improve within one month after adjustment to an appropriate dose, discontinue this medicine.

Child dose

Children and adolescents aged 6 years and older: Administer this medicine once a day, immediately after breakfast. The initial dose is 5mg per dose, administered once a day (in the morning) or 2 times a day (morning and noon). Increase the daily dose by 5 ~ 10mg each week according to the patient's treatment response and tolerability. The maximum daily dose of this medicine is 60mg.

This medication requires special caution in individuals with heart problems. In children and adolescents with structural heart abnormalities or heart disease, using this medication may increase the risk of sudden death. Adults with heart disease should also avoid using this medication. Patients with hypertension or cardiovascular disease should regularly monitor their blood pressure and heart rate and take appropriate precautions depending on their condition. A thorough medical history and physical examination should be conducted to check for heart conditions before taking this medication. If severe chest pain or unexplained fainting occurs during use, medical attention should be sought immediately. This medication may worsen symptoms in patients with mental illness or past psychiatric symptoms, so caution is needed. Particularly for patients with bipolar disorder, psychiatric evaluation is necessary before taking this medication, and if new psychotic symptoms or manic symptoms occur, discontinuation of the medication should be considered. Additionally, aggressive behavior or hostility may emerge, so behavior changes should be closely monitored during treatment. Suicidal thoughts or behaviors can appear suddenly, and if such symptoms occur, medical personnel should be informed immediately. Long-term use in children may cause growth delays, so renal and weight changes should be monitored regularly, and temporary discontinuation of the medication may be necessary. Patients with a history of seizures or abnormal EEGs may have a risk of seizures and should use the medication cautiously, discontinuing it if seizures occur. This medication may rarely cause visual disturbances, so consult with a doctor if any eye issues arise. It is not recommended for use in children under the age of 5 due to a lack of established safety and efficacy. There is a risk of drug abuse, so patients with a history of drug dependence or alcohol addiction should be careful not to change the dose arbitrarily. This medication can induce psychological dependence, requiring careful observation even during discontinuation. During treatment with this medication, painful erections may occur persistently, and if this symptom arises, immediate medical treatment should be sought. Symptoms of peripheral vascular disease, such as Raynaud's phenomenon, may rarely occur, so consult a physician if fingertips turn cold or change color. Do not take this medication in the following cases: If experiencing severe anxiety or tension, if allergic to this medication or its components, if having glaucoma or Tourette syndrome or tic disorders, if currently taking or have stopped taking MAO inhibitors within the last 14 days, if having severe heart disease or hyperthyroidism, if having pheochromocytoma or cerebrovascular disorders, if having certain gastrointestinal diseases, or if having inherited conditions such as fructose intolerance. Regularly monitor blood pressure and heart rate during the use of this medication, and periodically observe weight and height status. Continual evaluation of psychiatric state changes should also be conducted, paying close attention to possible drug abuse or misuse. This medication should be taken with or after meals and can be swallowed whole or the contents sprinkled in applesauce for immediate consumption. Caution is advised as dizziness can occur during driving or operating machinery. Store this medication out of reach of children and in its original container. If pregnant or breastfeeding, consult a physician before taking this medication. Weight loss in infants has been reported with use during breastfeeding, leading to considerations for discontinuation of nursing. In cases of overdose, symptoms such as central nervous system overstimulation, increased blood pressure, and increased heart rate may occur, requiring immediate medical attention.

Headache, diarrhea, appendicitis, abdominal pain, loss of appetite, insomnia, nasopharyngitis, restlessness, nausea, palpitations, tension, instability, aggression, excitement, anxiety, depression, irritability, abnormal behavior, mental disorder, auditory hallucinations, visual hallucinations, tactile hallucinations, anger, suicidal ideation, mood changes, crying, tics, exacerbation of existing tics or Tourette's syndrome, hypervigilance, sleep disorders, mania, disorientation, sexual dysfunction, suicide attempt, temporary depression, abnormal thinking, numbness, repetitive behaviors, hyperfocus, delusions, thought disorder, confusion, dependence, abuse, dizziness, movement disorders, psychomotor agitation, drowsiness, sedation, tremors, convulsions, chorea, ischemic neurological disorders, neuroleptic syndrome, cerebrovascular disorders, grand mal seizures, migraine, diplopia, blurred vision, visual accommodation disorders, mydriasis, arrhythmia, tachycardia, chest pain, angina, heart murmur, cardiac arrest, myocardial infarction, acute cardiac death, ventricular tachycardia, bradycardia, ventricular ectopy, ectopic beats, hypertension, cerebral artery occlusion, peripheral coldness, Raynaud's phenomenon, cough, sore throat, dyspnea, gastric discomfort, vomiting, dry mouth, constipation, elevated liver enzymes, hepatic coma, hair loss, pruritus, rash, urticaria, angioedema, hyperhidrosis, spots, erythema, polymorphic erythema, exfoliative dermatitis, fixed drug eruption, arthralgia, myalgia, myoclonus, muscle cramps, hematuria, menstrual irregularities, gynecomastia, fever, growth delay, fatigue, chest discomfort, abnormal high fever, changes in blood pressure and heart rate, weight loss, elevated alkaline phosphatase, elevated bilirubin, thrombocytopenia, abnormal leukocyte count, neuroexcitability, hypersensitivity, urticaria, fever, arthralgia, exfoliative dermatitis, necrotizing vasculitis, thrombocytopenic purpura, decreased appetite, dyskinesia, drowsiness, exacerbation of Tourette's syndrome, toxic psychosis, hepatic encephalopathy, cerebrovascular arteritis, occlusion, anemia, temporary feelings of depression, hair thinning, malignant neuroleptic syndrome

This medication should be stored in a sealed container as it may be sensitive to air or moisture. It is important to maintain a storage temperature between 1°C and 30°C to preserve the medication's effectiveness and safety over time.

Appearance

A hard capsule with a pink upper part and white lower part containing immediate-release white pellets and enteric-coated blue pellets.

Package unit

30 capsules (10 capsules/PTP x 3)