Serpen Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this drug should be adjusted for each patient, and it may be administered regardless of meals. ○ Adults: 1. Osteoarthritis (degenerative arthritis): Take 200 mg of celecoxib once daily, or 100 mg twice daily. 2. Rheumatoid arthritis: Take 100 mg or 200 mg of celecoxib twice daily. 3. Ankylosing spondylitis (AS): Administer 200 mg of celecoxib once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment with 400 mg daily, another treatment option should be considered. 4. Acute pain and primary dysmenorrhea: The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day of administration if needed. From the second day of administration, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment: In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be consulted with a doctor or pharmacist before use by individuals who consume large amounts of alcohol daily, as it may cause gastric bleeding. This medication may increase the risk of cardiovascular problems such as heart attack or stroke. Those with a history of cardiovascular disease or risk factors should use the minimum effective dose for the shortest duration possible. This medication can cause serious gastrointestinal problems such as ulcers, bleeding, or perforation in the stomach and intestines. Extra caution is advised for the elderly or individuals with a history of gastrointestinal diseases. This medication may cause allergic reactions; individuals with hypersensitivity to this medication or its components should not take it. Individuals with severe liver or kidney dysfunction, active gastric ulcer, inflammatory bowel disease, or heart failure should not use this medication. Pregnant or breastfeeding women should not take this medication, and women who may become pregnant should consult their doctor before usage. This medication can affect liver and kidney function, so individuals with a history of liver or kidney disease or the elderly should be cautious when using it. Regular monitoring of blood pressure, liver, and kidney function is necessary during treatment, and any unusual symptoms should be reported to a doctor immediately. This medication may interact with other drugs, so inform your doctor or pharmacist of any other medications you are taking. Dizziness or drowsiness may occur after taking this medication, so it is advisable to avoid driving or operating machinery. Long-term use of this medication may affect fertility; women planning to become pregnant should consult before starting treatment. If symptoms such as skin rash, fever, or blisters occur while taking this medication, stop taking it immediately and consult a doctor. Children and adolescents under 18 years should avoid using this medication as its safety and efficacy have not been established.

Gastrointestinal bleeding, cardiovascular thromboembolic reactions, myocardial infarction, stroke, upper and lower gastrointestinal perforations, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmias, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesiculobullous dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infections, visual disturbance, cataract, conjunctivitis, eye pain, glaucoma, retinal artery or vein occlusion, elevated serum creatinine, increased β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, elevated serum sodium, elevated serum potassium, increased BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, synovial cyst, arthralgia, osteoarthritis, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in various regions, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eosinophilic fasciitis, contact dermatitis, injection site reactions, skin nodules, headache, leg cramps, sensory deprivation, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicidal thoughts, anosmia, ageusia, exacerbation of allergies, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, weariness, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reactions, vasculitis, angioedema, hallucinations, cerebral hemorrhage, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, bile stasis, bile stasis hepatitis, jaundice, photosensitive reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, tubular interstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis, menstrual disorders, chest pain, thirst, ulcerative stomatitis, gastritis, allergies, low back pain, hyperlipidemia, hearing loss

This medication should be stored in a tightly sealed container to prevent air from entering, at room temperature between 15 to 30 degrees Celsius. Storing it this way helps maintain the medication's efficacy and prevents deterioration.

Appearance

A capsule filled with white to pale yellow powder with white top and bottom.

Package unit

30 capsules/bottle, 100 capsules/bottle