Ramsetron ODT 0.1 mg (Ramosetron Hydrochloride)

Adult dose

1 hour before administration of chemotherapy (cisplatin, etc.), administer 0.1 mg of Ramosetron Hydrochloride orally once daily. The administration period should be within 5 days for each cycle. Adjust dosage as appropriate based on symptoms.

This medication should not be used in patients who have demonstrated allergic reactions to this drug or any of its components. Patients taking other serotonin-related medications should use this drug with caution, particularly if they are taking selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs). Severe allergic reactions such as shock or anaphylaxis may occur while taking this drug. If such symptoms appear, discontinue use immediately and inform a healthcare professional. Seizures similar to epilepsy have been rarely reported, so patients with a history of epilepsy should use caution. Side effects such as abnormal liver function, headache, drowsiness, constipation, and fever may occur, so consult a doctor immediately if unusual symptoms appear. Although it dissolves in the mouth, it should be taken with water or saliva as it is not absorbed through the mucosa. It is primarily used to prevent or treat nausea and vomiting caused by chemotherapy, and additional treatment may be required if the effect is insufficient. There is a risk of developing a serious condition known as serotonin syndrome, so patients should be closely monitored when used in conjunction with other serotonergic drugs. This drug is metabolized in the liver; therefore, caution should be exercised when taken with certain medications as it may increase blood concentration and the risk of side effects. Women who are pregnant or may become pregnant should have the use of this medication carefully evaluated, and breastfeeding should be discontinued if using this drug. Safety for children and adolescents has not been established, so it is advisable not to use it. Elderly patients may have weakened bodily functions, so their condition should be closely monitored when dosing, and if any unusual symptoms appear, the administration should be stopped immediately. When removing this medication from its packaging, do not use your nails; use your fingertips to press it out, and damaged packaging does not affect its quality. Keep out of reach of children and be careful not to transfer to other containers. Animal studies have shown that administration of this drug during pregnancy may affect fetal development, so the risks and benefits should be carefully considered when used during pregnancy.

Serious side effects

Shock, symptoms similar to anaphylaxis (discomfort, chest discomfort, shortness of breath, wheezing, flushing, redness, itching, cyanosis, hypotension), seizure-like episodes

Mild side effects

• Headache
• heaviness in the head
• drowsiness
• constipation
• increased BUN
• elevated ALT
• elevated AST
• increased LDH
• elevated bilirubin
• fever

This medication is sensitive to light, so it should be stored in an opaque container. Additionally, it should be stored at room temperature between 1°C and 30°C to maintain its effectiveness.

Appearance

Convex round yellowish-orange orally disintegrating tablet

Package unit

10 tablets (1 tablet/Alu-Alu x 10)/case