Medication info
Pregatin Capsule 75 mg (Pregabalin)

Pregatin Capsule 75 mg (Pregabalin)

Prescription medicationHard capsule경구
Ingredient · strength
Pregabalin›75mg / 1 capsule
Manufacturer / importer
하나제약(주)
Appearance
A hard capsule with a red-brown upper part and a white lower part containing a white powder that is white or pale yellow.
Packaging
30 capsules/bottle, 200 capsules/bottle
Approval status
Active

MFDS item code 201109307 · Approved 2011.10.31 · Insurance code 657804790

Summary

Main use
Treatment of peripheral and central neuropathic pain, adjunctive therapy for partial seizures in epilepsy, improvement of fibromyalgia.
Who takes it
Adults · Children
Adult dose
This medication should be taken orally, divided into two doses daily, regardless of food intake. 1. Neuropathic pain - Peripheral neuropathic pain: Starting dose of 150 mg per day can be increased to 300 mg per day after 3 to 7 days, and may be further increased to a maximum of 600 mg at intervals of 7 days. - Central neuropathic pain: Starting dose of 150 mg per day can be increased to 300 mg after one week.
Child dose
Safety and efficacy data for children under 12 years of age and for adolescent patients aged 12-17 are insufficient, so administration is not recommended.

Ingredients

Manufacturer
하나제약(주)

Efficacy & effects

Treatment of peripheral and central neuropathic pain, adjunctive therapy for partial seizures in epilepsy, improvement of fibromyalgia.

  • Peripheral neuropathic pain
  • central neuropathic pain
  • partial seizures
  • fibromyalgia
View approved original text

This medication is used in adults for the treatment of peripheral and central neuropathic pain. It can also be used as an adjunctive therapy in patients with epilepsy who have partial seizures or secondary generalized symptoms. Additionally, it helps to relieve pain associated with fibromyalgia. It is effectively used in the treatment of various neurological disorders.

How to take

Adult dose

This medication should be taken orally, divided into two doses daily, regardless of food intake. 1. Neuropathic pain - Peripheral neuropathic pain: Starting dose of 150 mg per day can be increased to 300 mg per day after 3 to 7 days, and may be further increased to a maximum of 600 mg at intervals of 7 days. - Central neuropathic pain: Starting dose of 150 mg per day can be increased to 300 mg after one week.

Child dose

Safety and efficacy data for children under 12 years of age and for adolescent patients aged 12-17 are insufficient, so administration is not recommended.

Precautions

This medication may increase the risk of suicidal thoughts or behaviors, so patients taking it should inform their healthcare provider if they experience depression or mood changes. Patients with allergies to any components of this medication, or those with specific genetic issues such as lactose intolerance, should not use it. Diabetic patients should monitor their blood sugar levels closely as this medication can cause weight gain and changes in blood glucose levels. In case of severe allergic reactions such as angioedema, patients should stop taking the medication immediately and consult their healthcare provider. Elderly patients may experience increased dizziness or sedation, which could heighten the risk of falls and other accidents; caution is advised. Visual disturbances may occur; if symptoms arise, patients should inform their healthcare provider. Abrupt discontinuation of this medication can lead to withdrawal symptoms such as insomnia, headaches, and anxiety, so it should be tapered off gradually according to the healthcare provider's instructions. There is a risk of drug abuse, so patients with a history of substance abuse should take this medication with caution and report any signs of abuse immediately. Patients with decreased kidney function may require dosage adjustments. Patients with heart disease should consult their healthcare provider before taking this medication, especially those with severe heart failure. Caution is required if taking this medication alongside opioid analgesics due to an increased risk of central nervous system and respiratory depression. During early pregnancy, there is a risk of fetal malformations, so women who are pregnant or planning to become pregnant should consult their healthcare provider before taking this medication and should use effective contraceptive methods. Women who are breastfeeding should consider discontinuing either breastfeeding or the medication, as this drug can be passed into breast milk. Dizziness and sedation are common, so patients should avoid driving or operating hazardous machinery until they are sure of how the medication affects them. In case of overdose, symptoms such as confusion, drowsiness, and seizures may occur, so patients should seek appropriate medical treatment immediately. This medication should be kept out of reach of children, and transferring it to other containers should be avoided.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urinary changes.

Mild side effects

  • Dizziness
  • drowsiness
  • confusion
  • disorientation
  • irritability
  • depression
  • euphoria
  • decreased libido
  • insomnia
  • depersonalization
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  • hypersensitivity
  • restlessness
  • anxiety
  • mood swings
  • emotional lability
  • difficulty finding the right words
  • hallucinations
  • abnormal dreams
  • increased libido
  • panic attacks
  • impulsivity
  • apathy
  • ataxia
  • motor coordination disturbance
  • balance disorders
  • memory loss
  • attention deficits
  • memory impairment
  • tremors
  • speech disturbances
  • sensory disturbances
  • decreased sensation.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air or humidity. It is best to maintain storage temperatures between 15 and 30 degrees Celsius.

Appearance and packaging

Appearance

A hard capsule with a red-brown upper part and a white lower part containing a white powder that is white or pale yellow.

Package unit

30 capsules/bottle, 200 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.