Medication info
Pregabalin 150 mg Capsule

Pregabalin 150 mg Capsule

Prescription medicationHard capsule경구
Ingredient · strength
Pregabalin›150mg / 1 capsule
Manufacturer / importer
(주)바이넥스
Appearance
A hard capsule with a white or light yellow powder inside, with a white upper and lower part.
Packaging
100 capsules/bottle, 30 capsules/bottle
Approval status
Active

MFDS item code 201109286 · Approved 2011.10.31 · Insurance code 643103430

Summary

Main use
Treatment of peripheral and central neuropathic pain, adjunctive treatment of partial seizures in epilepsy, improvement of fibromyalgia.
Who takes it
Adults · Children
Adult dose
This medication is administered orally in divided doses of 1 day total dose 2 times daily, regardless of food. 1. Neuropathic Pain - Peripheral neuropathic pain: The starting dose may be 150 mg per day, with escalation to 300 mg per day possible after 3-7 days, and if necessary, further escalation up to a maximum of 600 mg per day can be conducted at 7-day intervals. - Central neuropathic pain: The starting dose may be 150 mg per day, with escalation to 300 mg per day possible after one week.
Child dose
Safety and efficacy data are insufficient for children under 12 years old and adolescents aged 12-17, so dosing is not recommended.

Ingredients

Manufacturer
(주)바이넥스

Efficacy & effects

Treatment of peripheral and central neuropathic pain, adjunctive treatment of partial seizures in epilepsy, improvement of fibromyalgia.

  • Peripheral neuropathic pain
  • central neuropathic pain
  • partial seizures
  • fibromyalgia
View approved original text

This medication is used in adults for the treatment of peripheral and central neuropathic pain. It is also used as an adjunct for partial seizures in epilepsy patients, regardless of the presence of secondary generalized symptoms. Additionally, it is effective in alleviating symptoms of fibromyalgia. It helps improve symptoms of various neurological diseases.

How to take

Adult dose

This medication is administered orally in divided doses of 1 day total dose 2 times daily, regardless of food. 1. Neuropathic Pain - Peripheral neuropathic pain: The starting dose may be 150 mg per day, with escalation to 300 mg per day possible after 3-7 days, and if necessary, further escalation up to a maximum of 600 mg per day can be conducted at 7-day intervals. - Central neuropathic pain: The starting dose may be 150 mg per day, with escalation to 300 mg per day possible after one week.

Child dose

Safety and efficacy data are insufficient for children under 12 years old and adolescents aged 12-17, so dosing is not recommended.

Precautions

This medication may increase the risk of suicidal thoughts or behaviors, so mood changes or symptoms of depression should be closely monitored during treatment. Patients with allergies to any ingredient in this medication or certain genetic conditions such as lactose intolerance should not take it. Diabetic patients may experience impacts on blood sugar control due to weight gain after taking this medication, so adjustments to antidiabetic medication dosages may be necessary. If serious allergic reactions such as angioedema occur, the medication should be immediately discontinued, and medical consultation should be sought. Elderly patients are at increased risk of falls due to dizziness or drowsiness that may occur while taking this medication. Blurred vision or other visual changes may occur, and if symptoms persist, discontinuation of the medication should be considered. Discontinuing this medication suddenly may lead to withdrawal symptoms such as insomnia, headache, nausea, and anxiety, so it should be tapered off gradually under a physician's guidance. Due to the risk of drug abuse, patients with a history of mental illness or substance abuse should take this medication with extra caution. Patients with impaired kidney function may require dose adjustments, and patients with heart disease should be monitored as well. When used in combination with central nervous system depressants such as opioids, there is a risk of respiratory depression, so care should be taken when taken together. Pregnant women should avoid this medication due to the risk of fetal malformation in early pregnancy, and women of childbearing potential should use effective contraception. Breastfeeding mothers should avoid this medication as it can be transmitted through breast milk. Caution is advised when engaging in hazardous activities such as driving or operating machinery due to the potential for dizziness or drowsiness. In case of overdose, symptoms such as confusion, drowsiness, and depression may occur, and treatment like hemodialysis may be required. This medication must be stored out of reach of children and should not be transferred to other containers. If serious adverse reactions, such as skin rashes, fever, or breathing difficulties occur, immediate discontinuation and medical advice should be sought.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with fever, blisters, skin peeling, pain in mouth/eyes mucosa, shortness of breath or difficulty breathing, asthma attacks, breathing abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden severe headache, thunderclap headache, seizures, altered consciousness, vision disturbances, paralysis, urinary retention

Mild side effects

  • Dizziness
  • drowsiness
  • confusion
  • impaired sense of direction
  • irritability
  • depression
  • euphoria
  • decreased libido
  • insomnia
  • derealization
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  • abnormal sensations
  • restlessness
  • anxiety
  • mood swings
  • emotional blunting
  • elevation of emotions
  • difficulty finding appropriate words
  • hallucinations
  • abnormal dreams
  • increased libido
  • panic attacks
  • impulsivity
  • apathy
  • ataxia
  • motor coordination disturbances
  • balance disorders
  • amnesia
  • attentional disturbances
  • memory impairment
  • tremor
  • speech disturbances
  • sensory disturbances
  • sensory loss

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. Additionally, it is important to store it at room temperature between 15 to 30 degrees Celsius to maintain its effectiveness.

Appearance and packaging

Appearance

A hard capsule with a white or light yellow powder inside, with a white upper and lower part.

Package unit

100 capsules/bottle, 30 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.