Glipham 2/500 mg Tablets

Adult dose

This medication is administered 1-2 times a day before or along with meals. The dosage can be adjusted according to each patient’s current therapy, efficacy, and tolerability, with appropriate blood sugar monitoring being conducted for this purpose. Typically, treatment is initiated at a low dose and adjusted based on the patient’s current medications and blood sugar levels. In clinical trials, the initial daily dosage was Glimepiride/Metformin Hydrochloride 2 mg/500 mg.

This medication may cause severe lactic acidosis or hypoglycemia, so administration should be discontinued if kidney function deteriorates rapidly. It is advisable to temporarily stop taking this medication and consult a doctor if symptoms such as dehydration, severe diarrhea, vomiting, or fever occur. Patients with poor kidney function or the elderly should use this medication with special caution and undergo regular kidney function tests. Patients with cardiovascular diseases or those who have experienced myocardial infarction in the past should be cautious when using this medication. This medication should not be administered to insulin-dependent diabetes patients, those with acute metabolic acidosis, severe liver dysfunction, pregnant or breastfeeding women. Patients at higher risk of hypoglycemia, those with poor nutritional status, and heavy alcohol consumers should be particularly cautious when using this medication. During the course of this medication, patients should be well-informed about symptoms of hypoglycemia and lactic acidosis, and should alert a doctor immediately if symptoms occur. Gastrointestinal side effects such as diarrhea, nausea, vomiting, and abdominal bloating may occur, although they are usually temporary. If skin rashes or allergic reactions occur, immediate medical attention should be sought. This medication has many drug interactions, so patients should inform their doctor or pharmacist of any other medications they are taking. Pregnant or breastfeeding women are advised not to use this medication and should switch to insulin therapy if necessary. Children and the elderly require special attention and regular testing when using this medication. In the case of overdose, severe hypoglycemia or lactic acidosis may occur, requiring immediate emergency treatment. This medication should be taken in conjunction with regular meals and exercise, and blood sugar and kidney function should be monitored regularly. Caution is needed when driving or operating machinery as symptoms of hypoglycemia or drowsiness may occur. Store this medication out of the reach of children, and do not transfer it to other containers.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness, high fever with severe rash, blisters, skin peeling, pain in oral or ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory distress accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headache, lightning headaches, seizures, confusion of consciousness, visual disturbances, paralysis, significantly reduced urine output

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal bloating
• loss of appetite
• indigestion
• constipation
• abdominal pain
• nausea
• upper abdominal fullness or pressure

This medication should be stored in a tightly sealed container to prevent air from entering, and it is best kept at room temperature between 1 and 30 degrees Celsius. By storing it this way, the effectiveness of the medication can be maintained and used safely.

Appearance

White oblong film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle, 30 tablets/box [(10 tablets/PTP x 3)]