Medication info
Pregabalin Capsule 150mg (Pregabalin)

Pregabalin Capsule 150mg (Pregabalin)

Prescription medicationHard capsule경구
Ingredient · strength
Pregabalin›150mg / 1 capsule
Manufacturer / importer
동국제약(주)
Appearance
Hard capsule with a white upper half and a white lower half containing white powder that is white or pale yellow.
Packaging
30 capsules/bottle, 100 capsules/bottle
Approval status
Active

MFDS item code 201109225 · Approved 2011.10.27 · Insurance code 653402540

Summary

Main use
Relief of peripheral and central neuropathic pain, adjunctive treatment for partial seizures in epilepsy, improvement of fibromyalgia.
Who takes it
Adults · Children
Adult dose
This medication is pregabalin and is taken orally in two divided doses per day, regardless of food. 1. Neuropathic pain - Peripheral and central neuropathic pain: Starting dose is 150 mg per day, which can be increased to 300 mg depending on response and tolerance after 3 days to 1 week. Further increments may be considered to a maximum of 600 mg per day at intervals of 7 days if necessary. 2. Epilepsy - Starting dose: 150 mg per day.
Child dose
The safety and efficacy data are insufficient for children under 12 years and adolescents aged 12-17 years, thus administration is not recommended.

Ingredients

Manufacturer
동국제약(주)

Efficacy & effects

Relief of peripheral and central neuropathic pain, adjunctive treatment for partial seizures in epilepsy, improvement of fibromyalgia.

  • Peripheral neuropathic pain
  • central neuropathic pain
  • partial seizures
  • fibromyalgia.
View approved original text

This medication is used for the treatment of peripheral and central neuropathic pain in adults. Additionally, it is effective as an adjunct for partial seizures in patients with epilepsy, applicable in cases with or without secondary general symptoms. It also helps alleviate symptoms of fibromyalgia. Overall, it is widely used for the improvement of neuralgia and myalgia symptoms.

How to take

Adult dose

This medication is pregabalin and is taken orally in two divided doses per day, regardless of food. 1. Neuropathic pain - Peripheral and central neuropathic pain: Starting dose is 150 mg per day, which can be increased to 300 mg depending on response and tolerance after 3 days to 1 week. Further increments may be considered to a maximum of 600 mg per day at intervals of 7 days if necessary. 2. Epilepsy - Starting dose: 150 mg per day.

Child dose

The safety and efficacy data are insufficient for children under 12 years and adolescents aged 12-17 years, thus administration is not recommended.

Precautions

This medication may increase the risk of suicidal thoughts or behavior, so it is important to closely monitor for mood changes or depressive symptoms during treatment. It should not be taken if there is hypersensitivity to the drug or specific genetic disorders related to lactose intolerance. Diabetic patients should be cautious as weight gain may necessitate adjustments in blood sugar-controlling medication. If symptoms of angioedema occur, such as swelling of the face or around the mouth, you should stop taking this medication immediately and consult a healthcare professional. Elderly patients may be at increased risk of falls due to dizziness or drowsiness caused by this medication. Transient blurred vision or changes in vision may occur; if symptoms persist, consult a doctor. Abrupt discontinuation of this medication may lead to withdrawal symptoms such as insomnia, headache, and anxiety, so doses should be gradually reduced under medical supervision. Patients with a history of substance abuse should be particularly cautious due to the risk of drug misuse. Patients with impaired kidney function may require dose adjustments. Patients with cardiovascular disease should be cautious when taking this medication, and those with severe heart failure should use it with caution. When taken concurrently with opioid analgesics, central nervous system depressant effects may be intensified, so caution is advised. Patients with impaired respiratory function or the elderly should consult healthcare professionals to adjust the dose due to the risk of severe respiratory depression. In early pregnancy, it may pose risks to the fetus; therefore, women who are pregnant or planning to become pregnant should consult a doctor and use effective contraception. Lactating women should consult healthcare professionals regarding the discontinuation of breastfeeding or medication since this drug can be passed into breast milk. It is advisable to avoid hazardous activities such as driving or operating machinery during dizziness or drowsiness after taking this medication. If significant rash or allergic reactions occur during treatment, stop taking this medication immediately and inform your healthcare provider. In the event of overdose, symptoms like confusion, drowsiness, and seizures may appear, and immediate medical attention is necessary.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, Stevens-Johnson syndrome, toxic epidermal necrolysis, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache.

Mild side effects

  • Dizziness
  • drowsiness
  • confusion
  • loss of direction
  • irritability
  • depression
  • euphoria
  • decreased libido
  • insomnia
  • depersonalization
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  • dysesthesia
  • restlessness
  • anxiety
  • mood swings
  • emotional lability
  • difficulty finding appropriate words
  • hallucinations
  • abnormal dreams
  • increased libido
  • panic attacks
  • impulsivity
  • apathy
  • ataxia
  • motor coordination disturbances
  • balance disorders
  • amnesia
  • attentional deficits
  • memory impairment
  • tremor
  • dysarthria
  • sensory abnormalities
  • sensory loss.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, and it is best stored at room temperature between 15 and 30 degrees Celsius. This storage method helps maintain the efficacy of the medication for a longer period.

Appearance and packaging

Appearance

Hard capsule with a white upper half and a white lower half containing white powder that is white or pale yellow.

Package unit

30 capsules/bottle, 100 capsules/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.