Glimem 2/500 mg Tablets

Adult dose

This medication is administered 1 to 2 times daily just before meals or with meals. The dosage can be adjusted based on each patient's current treatment regimen, efficacy, and tolerance, and blood sugar monitoring should be conducted. Treatment typically starts at a lower dose and is adjusted as needed. The initial dose is glymeperide/metformin hydrochloride 2 mg/500 mg, and dosage can be gradually increased based on blood sugar monitoring results up to a maximum of 8 mg/2000.

This medication can cause severe lactic acidosis or hypoglycemia; therefore, it should be discontinued if renal function worsens rapidly. Caution is especially needed if there are signs of dehydration or if the patient is taking medications that may affect kidney function. Patients with cardiovascular disease may have an increased risk of cardiovascular mortality, thus requiring careful monitoring. This medication should not be administered to patients with insulin-dependent diabetes or acute metabolic acidosis. It should also not be used in patients with severely impaired liver function, those on hemodialysis, pregnant women, or nursing mothers. Patients with moderate to severe renal impairment or those undergoing specific tests (e.g., tests requiring iodinated contrast materials) should avoid this medication. Caution should be exercised in patients at high risk for hypoglycemia, such as those with poor nutritional status, irregular eating habits, elderly patients, and those with reduced liver function. Gastrointestinal disturbances may occur during the initial stages of treatment, though these are usually transient. Regular laboratory tests are needed as allergic reactions, blood abnormalities, and vitamin B12 deficiency may arise. This medication can interact with other medications, so it is crucial to inform healthcare providers of any ongoing medications being taken. Pregnant or nursing patients should refrain from taking this medication and switch to insulin therapy if necessary. When administered to children or the elderly, careful observation of kidney function and overall condition is essential. Overdose may result in hypoglycemia, and immediate contact with a healthcare facility and appropriate treatment is required. Regular checks of blood sugar control should be conducted, and if any abnormal symptoms arise, immediate consultation with a physician is needed. Caution is necessary when driving or operating machinery as hypoglycemia or decreased agility may occur. This medication should be stored out of reach of children and should not be transferred to other containers.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, chest tightness, shock, hypotension, severe allergic reaction symptoms, severe lactic acidosis, severe liver dysfunction (liver failure, jaundice), serious blood abnormalities (thrombocytopenic purpura, pancytopenia), coma due to severe hypoglycemia, serious neurological symptoms (confusion, seizures, severe headaches, visual disturbances, paralysis), cardiac arrest, severe edema, acute deterioration of renal function, acute.

Mild side effects

Gastrointestinal symptoms (diarrhea, nausea, vomiting, abdominal distension, loss of appetite, indigestion, constipation, abdominal pain), transient dose reduction may be beneficial for gastrointestinal symptoms, metallic taste, visual impairment, taste disorders, thrombocytopenia, leukopenia, hemolytic anemia, erythropenia, agranulocytosis, pancytopenia, vitamin B12 decrease and deficiency, increased liver enzymes, hepatitis, allergic vasculitis, skin photosensitivity, and blood.

This medication should be kept tightly closed to protect it from air and moisture, stored safely at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication for a longer period.

Appearance

White oblong film-coated tablets

Package unit

30 tablets/PTP