Glimid M Tablet

Adult dose

This medication is administered 1 to 2 times daily before meals or with meals. Typically, treatment is started at a low dose, and the dosage may be adjusted considering the patient's current medications and blood glucose levels. In clinical trials, the initial daily dose was Glimepiride/Metformin Hydrochloride 2mg/500mg, and based on blood glucose monitoring results, the dosage was gradually increased up to Glimepiride/Metformin Hydrochloride 8mg/2000mg.

This medication may cause severe lactic acidosis or hypoglycemia; therefore, it may be dangerous for patients with significantly impaired kidney function. If kidney function diminishes, the components of this medication can accumulate in the body, increasing the risk of lactic acidosis, so kidney function should be regularly checked to ensure it is normal. If dehydration symptoms or severe diarrhea, vomiting, fever, etc. occur, it is recommended to temporarily stop taking this medication and consult a doctor. Patients at risk of cardiovascular diseases need to be cautious when taking this medication and should thoroughly discuss treatment options with their physician. If there are specific illnesses or if pregnant, or if liver or kidney function is severely impaired, this medication should not be taken. Patients at high risk for hypoglycemia, malnourished patients, elderly persons, etc. need more careful observation and management when taking this medication. Initial use may cause gastrointestinal disturbances (diarrhea, nausea, vomiting, etc.), but these are mostly temporary, and taking the medication with meals can help alleviate symptoms. If any allergic reactions or severe side effects occur, inform the doctor immediately, and if hypoglycemia symptoms develop, quickly consume sugar to control it. This medication may interact with other drugs; therefore, inform healthcare professionals about any other medications being taken. During pregnancy or breastfeeding, it is advisable to avoid this medication and consider switching to insulin therapy if necessary. Caution is necessary with children and the elderly; particularly, elderly patients commonly have reduced kidney function, making regular kidney function assessments essential. In case of overdose, severe hypoglycemia or lactic acidosis may occur, requiring immediate medical attention. While taking this medication, regular monitoring of blood sugar, kidney function, and hematological tests is recommended, and it is also good to monitor for vitamin B12 deficiency. Be cautious while driving or operating machinery as hypoglycemia or agility impairment can occur.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, severe allergic reactions, severe rash, blisters, skin peeling, pain in oral/ocular mucous membranes, severe dermatological reaction, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, skin or eyes turning yellow (jaundice), extreme lethargy, liver dysfunction (jaundice), sudden and severe headaches, lightning headaches, seizures, loss of consciousness.

Mild side effects

Diarrhea, nausea, vomiting, abdominal bloating, reduced appetite, dyspepsia, constipation, abdominal pain, taste disturbance, thrombocytopenia, leukopenia, hemolytic anemia, erythrocytopenia, agranulocytosis, pancytopenia, vitamin B12 deficiency, elevated liver enzymes, liver function impairment, hepatitis, allergic reactions (erythema, itching, rash), allergic vasculitis, photosensitivity, decreased serum sodium, hypothyroidism, diarrhea.

This medication should be stored in a tightly closed container protected from air and moisture. It is important to maintain storage temperatures between 1 to 30 degrees Celsius.

Appearance

White, rectangular film-coated tablet

Package unit

30 tablets/box [30 tablets (10 tablets/PTP X 3)]