Gerid M Tablet

Adult dose

This medication is taken 1 to 2 times a day before or with meals. The dosage may be adjusted based on each patient's current treatment regimen, efficacy, and tolerability, and proper blood sugar monitoring is necessary. The initial dosage is Glimepiride/Metformin Hydrochloride 2mg/500mg, and it may be increased gradually based on blood sugar monitoring up to 8mg/2000mg. In general, single-drug glimepiride is administered at a daily dosage of 4mg.

This medication carries a risk of severe lactic acidosis and hypoglycemia, therefore it should be avoided in patients with rapidly declining kidney function. In cases of dehydration, it is advisable to temporarily discontinue this medication and consult a physician. When used in combination with drugs that may cause acute renal impairment, kidney function must be closely monitored. Excessive alcohol intake, liver dysfunction, uncontrolled diabetes, prolonged fasting, etc., can also increase the risk of lactic acidosis and should be approached with caution. Patients taking this medication and their caregivers should be sufficiently educated about the symptoms of lactic acidosis, and if any suspicious symptoms occur, the medication should be stopped immediately, and emergency treatment should be sought. Kidney function should be evaluated before treatment initiation and regularly thereafter, especially in elderly patients or those at risk of declining kidney function, requiring greater caution. The risk of cardiovascular disease may be increased, so a thorough discussion regarding the benefits and risks of this medication should be held with a physician. This medication is not to be administered to patients with insulin-dependent diabetes, acute metabolic acidosis, severe liver or kidney dysfunction, and pregnant or breastfeeding women. The use of iodinated contrast agents before and after examinations should lead to the discontinuation of this medication until kidney function is re-evaluated. Patients at high risk of hypoglycemia, malnutrition or irregular eating patterns, or those engaging in vigorous exercise should be monitored particularly closely. Gastrointestinal symptoms (diarrhea, nausea, vomiting, etc.) may occur during the use of this medication; most are temporary but should be addressed with a physician if severe. Should any allergic reactions or blood abnormalities occur, medical personnel must be notified immediately, and in severe cases, discontinuation of the medication is warranted. This medication may interact with other drugs; therefore, if taking other medications, be sure to inform a physician or pharmacist. Pregnant or breastfeeding women should not take this medication and should be switched to insulin therapy if necessary. Care should be taken when administering to children and elderly; particularly elderly patients will require dose adjustments and regular assessments due to potential kidney function decline. In case of overdose, hypoglycemia or lactic acidosis may occur; if symptoms arise, emergency treatment should be sought immediately. While taking this medication, it is essential to engage in regular meals and exercise, as well as undergo periodic blood sugar and kidney function tests. Caution is needed when operating vehicles or machinery due to reduced attention from hypoglycemia or hyperglycemia.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, lactic acidosis, hypoglycemia, serious thrombocytopenia associated with thrombocytopenic purpura, liver damage (cholestasis, jaundice), cardiac arrest, severe allergic reactions, severe skin reactions, respiratory problems, liver abnormalities (jaundice), severe neurological symptoms, severe edema or urinary abnormalities.

Mild side effects

Diarrhea, nausea, vomiting, abdominal bloating, loss of appetite, indigestion, constipation, abdominal pain, gastrointestinal symptoms, metallic taste, visual impairment, taste disturbances, erythema, itching, rash, nausea, vomiting, a feeling of fullness or pressure in the upper abdomen, abdominal pain, thrombocytopenia, leukopenia, hemolytic anemia, erythropenia, agranulocytosis, pancytopenia, vitamin B12 reduction, increased liver enzymes, hepatitis, allergic vasculitis, urticaria.

This medication should be stored in a tightly closed container to prevent airflow, and it is recommended to keep it at room temperature between 1 and 30 degrees. Storing it this way helps maintain the effectiveness of the medication for an extended period.

Appearance

White, rectangular, film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle