Diagril M Tablet 2/500 mg

Adult dose

This medication is administered 1 to 2 times a day before or with meals. The dosage may be adjusted based on the treatment regimen, effectiveness, and tolerance for each patient, and blood sugar monitoring is necessary. The initial dose is Glymeperide/Metformin Hydrochloride 2 mg/500 mg, which can be gradually increased to a maximum of 8 mg/2000 mg. The single-agent glymeperide generally does not provide additional effects when dosed over 4 mg per day.

This medication can cause severe lactic acidosis or hypoglycemia, so it should be discontinued and a doctor consulted if there is a sudden decline in kidney function or signs of dehydration. It is contraindicated for patients with reduced kidney function, and usage should be temporarily halted in situations where kidney function may change. Increased risk of cardiovascular diseases may occur, so cardiovascular status should be closely monitored during therapy with this medication. It should not be administered to specific patient groups such as those with insulin-dependent diabetes, acute metabolic acidosis, severe liver dysfunction, pregnant or breastfeeding women, or patients with severe renal impairment. Particular caution is required for elderly patients, malnourished individuals, those with irregular meals, those engaging in vigorous exercise, and alcohol consumers due to a higher risk of hypoglycemia; hypoglycemic symptoms should be closely monitored at the beginning of treatment. Digestion-related symptoms such as diarrhea, nausea, vomiting, and abdominal bloating may occur, and if these symptoms are severe, a doctor should be consulted. Any allergic reactions or skin rashes, and symptoms of blood abnormalities should be reported immediately to a healthcare professional. This medication may interact with other drugs; therefore, any concurrent medications should be disclosed to the doctor or pharmacist. Pregnant or breastfeeding individuals should avoid taking it, and should switch to insulin therapy if necessary. Safety has not been adequately confirmed in children and adolescents, so it should be administered to pediatric patients cautiously. Elderly individuals may carry an increased risk of side effects due to decreased kidney function, so dosage adjustment and kidney function testing are necessary. Regular monitoring of blood sugar levels, kidney function, blood tests, etc. should be conducted to detect and manage abnormalities early. In cases of overdose, severe hypoglycemia or lactic acidosis may occur, requiring immediate medical treatment; in emergency situations, measures to rapidly elevate blood sugar levels must be taken. Excessive alcohol consumption should be avoided while taking this medication, and stopping the medication temporarily is advisable in the event of acute illness or surgery. Care should be taken when driving or operating machinery due to the risk of accidents from hypoglycemia.

Serious side effects

Urticaria, severe swelling (edema), difficulty breathing, hypotension, severe allergic reactions, liver abnormalities (jaundice, yellowing of the skin or eyes), lactic acidosis, severe skin reactions (severe rashes with fever, blisters, skin peeling, pain in the mouth/eyes), severe neurological symptoms (severe headache, seizures, confusion, visual disturbance, paralysis), severe hematological abnormalities (severe thrombocytopenia associated with thrombocytopenic purpura...

Mild side effects

Gastrointestinal symptoms (diarrhea, nausea, vomiting, abdominal bloating, loss of appetite, indigestion, constipation, abdominal pain), temporary effects due to dosage reduction, visual impairment related to blood sugar changes, taste disturbance, decreased TSH levels in hypothyroidism, magnesium deficiency in case of diarrhea, encephalopathy, hair loss, weight gain, allergy-like reactions (erythema, itching, rash, etc.), hematological abnormalities (thrombocytopenia, leukopenia, hemolytic anemia, red...

This medication should be stored in a tightly closed container to prevent air intrusion and should be kept at a temperature ranging from 1 to 30 degrees Celsius. Storing it this way helps maintain the effectiveness of the medication for a longer period.

Appearance

White oblong film-coated tablets

Package unit

30 tablets/bottle