Gleam Tablet 2/500 mg

Adult dose

This medication is administered 1 to 2 times a day just before meals or with meals. Typically, treatment is initiated at a low dose, and the dose may be adjusted based on the patient's current medication and blood sugar levels. In clinical trials, the initial daily dosage was 2 mg/500 mg of glimipiride/metformin hydrochloride, and based on blood sugar monitoring results, the dosage may be gradually increased up to 8 mg/2000 mg. For single-agent glimipiride,

This medication can cause severe lactic acidosis and hypoglycemia, so it should be discontinued and a doctor consulted, especially in cases of acute kidney function decline. Caution is necessary when using this medication if there are signs of dehydration or if taking medications that may affect kidney function, and depending on the situation, the medication may need to be temporarily suspended. Patients at risk for cardiovascular diseases should be fully consulted with their healthcare providers about the potential increase in cardiovascular mortality associated with taking this medication. Patients with insulin-dependent diabetes, acute metabolic acidosis, severe liver or kidney dysfunction, and women who are pregnant or breastfeeding should not take this medication. Elderly patients, malnourished individuals, and those who consume excessive alcohol should be monitored carefully when taking this medication due to a higher risk of hypoglycemia. Gastrointestinal symptoms (such as diarrhea, nausea, and vomiting) may commonly occur at the start of treatment; however, these are mostly transient and can be alleviated by taking the medication with meals or adjusting the dosage. This medication may cause allergic reactions, hematological abnormalities, vitamin B12 deficiency, etc., so if any abnormal symptoms occur, it is essential to notify a healthcare professional immediately. Regular monitoring of kidney function, blood sugar, and hematological values should be conducted to monitor the effectiveness and side effects of the medication, particularly in the elderly, who should have kidney function tests done frequently. The medication may interact with other drugs, so it is vital to consult the healthcare provider before starting or stopping any new medications. If pregnant or breastfeeding, this medication should be avoided as it may harm the fetus or infant; insulin therapy should be considered instead if necessary. In case of overdose, severe hypoglycemia or lactic acidosis may occur, necessitating immediate medical attention for appropriate treatment. Caution is also needed when driving or operating machinery due to the potential risk of accidents from hypoglycemia or other side effects. This medication should be kept out of the reach of children, and transferring it to another container should be avoided to prevent degradation of quality or accidents.

Serious side effects

Hives, swelling, severe allergic reactions, tightness in the chest, difficulty breathing, severe thrombocytopenia associated with thrombocytopenic purpura, cardiac arrest, lactic acidosis, hypoglycemia, liver abnormalities (jaundice), severe skin adverse reactions (severe rash, blisters, peeling skin, pain in mucous membranes of the mouth/eyes), serious neurological symptoms (confusion, paralysis), respiratory problems (shortness of breath or difficulty breathing, asthma attacks), severe swelling or urination issues

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal bloating
• loss of appetite
• indigestion
• constipation
• abdominal pain
• nausea
• fullness or pressure

This medication should be stored in a tightly sealed container to protect it from air and moisture, and the storage temperature should be maintained at room temperature between 1 to 30 degrees Celsius. Thus, it is essential to avoid direct sunlight and extreme temperatures, storing it in a cool place.

Appearance

White rectangular film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP × 3]