GliphoMin M Tablet 1/250 mg

Adult dose

This medication is administered 1 to 2 times a day before meals or with meals. The dosage can be adjusted based on each patient's current treatment regimen, efficacy, and tolerability, and appropriate blood sugar monitoring is necessary. Usually, treatment is initiated at a low dose, and dosage adjustments can be made considering the patient's current medications and blood sugar levels. In clinical trials, the initial daily dosage was 2 mg/500 mg of glimepiride/metformin hydrochloride.

This medication can cause severe lactic acidosis or hypoglycemia, so caution is necessary. Especially if kidney function decreases rapidly, the medication can accumulate in the body, raising the risk of lactic acidosis. If dehydration symptoms are present, it is advisable to temporarily halt the use of this medication and consult a physician. Extra caution is needed when taken with other medications that may worsen kidney function. Excessive alcohol intake, liver dysfunction, and poorly controlled diabetes can also increase the risk of lactic acidosis. This medication is not to be given to patients with insulin-dependent diabetes, acute metabolic acidosis, or severe liver or kidney dysfunction. It is also recommended that pregnant or breastfeeding women avoid using this medication. In elderly patients or those with diminished kidney function, dosage adjustment and regular monitoring of kidney function are necessary. Patients who are starting the medication or who are at a higher risk for hypoglycemia should be closely monitored for hypoglycemic symptoms. Hypoglycemic symptoms may include headaches, fatigue, trembling, and confusion, which in severe cases can lead to loss of consciousness. Gastrointestinal disturbances (nausea, diarrhea, etc.) may occur but usually resolve over time. It is important to regularly monitor blood sugar levels, kidney function, and vitamin B12 levels during the use of this medication. There may be interactions with other medications, so it is essential to inform your physician or pharmacist of any ongoing medications. Caution is particularly warranted when used with medications that may affect kidney function or enhance or reduce blood sugar-lowering effects. When driving or operating machinery, be careful of the risks of hypoglycemia or impaired agility. In case of overdose, hypoglycemia or lactic acidosis may occur, necessitating immediate consultation with healthcare professionals for appropriate treatment. This medication should be avoided in children and pregnant women, as its safety has not been established. During the use of this medication, regular meals, exercise, and blood sugar management are necessary, and immediate consultation with a physician is advised if symptoms or adverse reactions occur.

Serious side effects

Urticaria, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/eye mucosa, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities accompanied by coughing and fever, jaundice (yellowing of the skin or eyes), extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, significantly reduced urine output

Mild side effects

Diarrhea, nausea, vomiting, abdominal bloating, loss of appetite, indigestion, constipation, abdominal pain, nausea, vomiting, feeling of fullness or pressure in the upper abdomen, abdominal pain, metallic taste, visual impairment, taste disturbances, erythema, itching, rash, thrombocytopenia, leukopenia, hemolytic anemia, erythrocytopenia, granulocytopenia, agranulocytosis, pancytopenia, decreased vitamin B12, increased liver enzymes, liver function impairment, hepatitis, allergic vasculitis, skin

This medication should be stored in a sealed container to prevent air ingress, and the storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the medication's efficacy for a longer period.

Appearance

White oblong film-coated tablet

Package unit

30 tablets (10 tablets/PTP x 3)