Glipiron M Tablets 2/500 milligrams

Adult dose

This medication is taken 1 to 2 times a day before meals or with meals. The dosage can be adjusted based on each patient's current treatment regimen, efficacy, and tolerance, requiring appropriate blood glucose monitoring. Typically, treatment is initiated at a low dose, and dosage adjustments can be made based on the patient's current medication and blood glucose levels. In clinical trials, the initial daily dose was Glymefide/Metformin Hydrochloride

This medicine may pose a risk of severe lactic acidosis or hypoglycemia; thus, especially in cases of rapid decline in kidney function, discontinuation of the medication is necessary. It is important to temporarily discontinue this medication and consult a physician if there is dehydration or severe diarrhea, vomiting, or fever. Patients with a risk of cardiovascular disease should use this medication with caution as it may be associated with an increased rate of cardiovascular mortality. This medication should not be administered to patients with insulin-dependent diabetes, severe hepatic dysfunction, severely impaired kidney function, pregnant women, or nursing mothers. During the initial dosing, the risk of hypoglycemia is high; therefore, careful monitoring of meal status and blood sugar is required, especially in elderly patients or those with poor nutritional status, patients engaging in intense exercise, and those with high alcohol consumption. Common gastrointestinal side effects of this medication include gastrointestinal disorders, nausea, vomiting, diarrhea, but most of these are temporary and improve gradually. If serious allergic reactions or skin rashes develop, notify a physician immediately. Long-term use may result in vitamin B12 deficiency, necessitating regular blood tests. In patients with impaired kidney function, there is an increased risk of accumulation and lactic acidosis from this medication, so regular kidney function tests should be performed, and discontinuation should be considered if necessary. The combination with other medications may affect blood sugar control; therefore, any concurrent medications should be reported to healthcare providers. It is safer for women who are pregnant or planning to become pregnant, as well as nursing women, to avoid this medication. Overdose may cause hypoglycemia and lactic acidosis; immediate contact with a medical facility and appropriate treatment are required. Caution is necessary during driving or operating machinery due to the potential for hypoglycemia or other side effects. The safety and efficacy of this medication in children have not been established; thus, special care is needed when administering to children. During the intake of this medication, regular meals and exercise, along with routine monitoring of blood sugar and kidney function, are essential for managing therapeutic effects and side effects.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory problems accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, liver abnormalities (jaundice), sudden appearance of

Mild side effects

• Diarrhea
• nausea
• vomiting
• abdominal distension
• loss of appetite
• indigestion
• constipation
• abdominal pain
• gastrointestinal symptoms
• taste disturbance

This medication should be stored in a tightly sealed container to keep out air and moisture, and it is best to keep it at room temperature between 1 to 30 degrees Celsius. Storing it this way helps maintain the efficacy of the medication.

Appearance

White rectangular film-coated tablets

Package unit

30 tablets/box [(10 tablets/PTP*3)]