Cox-2 Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient, and it may be taken with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) : Take celecoxib 200 mg once daily, or 100 mg twice daily in divided doses. 2. Rheumatoid arthritis : Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS) : Administer celecoxib 200 mg once daily, or 100 mg twice daily in divided doses. If no effect is observed after 6 weeks, a dose of up to 400 mg daily may be administered. If no effect is observed after 6 weeks of treatment with 400 mg daily, consider another treatment option. 4. Acute pain and primary dysmenorrhea : The recommended initial dose is celecoxib 400 mg; an additional 200 mg may be given on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment : In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be discussed with a doctor or pharmacist if the person taking it regularly consumes more than three drinks a day. This medication can increase the risk of cardiovascular diseases, myocardial infarction, and stroke, so it should be used at the lowest effective dose and for the shortest duration necessary. Gastrointestinal adverse reactions such as gastrointestinal bleeding, ulcers, or perforations may occur, so particularly caution is needed for those with a history of gastrointestinal diseases or the elderly. Patients with an allergy to this medication or certain conditions (liver impairment, kidney impairment, active peptic ulcer, congestive heart failure, etc.) should not take it. Patients with a history of liver impairment, kidney impairment, asthma, heart failure, or hypertension should use this medication cautiously, and regular testing as directed by a physician is necessary. This medication may have various side effects, including indigestion, vomiting, headache, dizziness, skin rash, hypertension, and edema, so if any abnormal symptoms occur, consult a doctor immediately. This medication can affect liver and kidney function, so regular blood tests and liver and kidney function tests should be performed if taken for a long time. Pregnant women or those who may become pregnant, as well as nursing mothers, should not use this medication, and women planning to become pregnant should consult a doctor before taking it. This medication may interact with other drugs, so it is crucial to inform your doctor or pharmacist about any medications you are taking. Dizziness or drowsiness may occur, so it is advisable to avoid driving or operating machinery after taking this medication. This medication has not been established for safety and efficacy in children and adolescents, so it is not used in these populations. Elderly patients may have reduced liver and kidney function, and special care is needed while taking this medication; start with a lower dose if their body weight is low. This medication should be stored out of the reach of children, and it is recommended not to transfer it to another container.

Gastrointestinal bleeding, cardiovascular thrombotic reaction, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcer, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, coughing, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial edema, influenza-like illness, injury, taste disorder, albuminuria, cystitis, hematuria, dysuria, polyuria, kidney stones, urinary incontinence, urinary tract infection, visual confusion, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, headache, leg cramps, hypertonia, sensory impairment, migraine, neuralgia, neuropathy, sensory abnormality, cerebral infarction, aseptic meningitis, ataxia, suicide, anosmia, ageusia, exacerbation of allergy, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, septicemia, sudden death, anaphylactoid reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized bullous fixed drug eruption, fixed drug eruption, menstrual disorders, female infertility, chest pain, thirst, ulcerative stomatitis, gastritis, lumbago, hyperlipidemia, diabetes, weight gain, fracture, arthralgia, RA factor positive, herpes zoster, pneumonia, respiratory distress, hearing loss, anaphylactic reaction, hallucinations, cerebral hemorrhage, vasculitis, pulmonary embolism, gastrointestinal bleeding, hepatitis, acute renal failure, hyponatremia

This medication should be stored in a container that is tightly closed to prevent air from entering and kept at room temperature between 15 to 30 degrees Celsius. Storing it this way can help maintain the efficacy of the medication for a longer period.

Appearance

A capsule with a fluorescent yellow upper part and a white lower part filled with a white to pale yellow powder

Package unit

30 capsules/bottle, 200 capsules/bottle