CoolPrep San

Adult dose

In adults aged 18 years and older, administration is as follows: 1) Divided administration method: On the evening before the colonoscopy, consume the prepared solution of 1L over 1 hour (250mL 1 cup every 15 minutes) and drink 0.5L of water. The next morning, consume the prepared solution of 1L over 1 hour and drink 0.5L of water. This process must be completed at least 1 hour before the start of the colonoscopy. 2) Non-divided administration (evening administration) method: On the evening before the colonoscopy, around 6 PM, consume the prepared solution of 1L over 1 hour (250mL 1 cup every 15 minutes), and 1.5 hours later, consume another prepared solution of 1L over 1 hour. Additionally, drink 1L of water during the evening.

This medication may rarely induce generalized tonic-clonic seizures even in patients without a history of seizures, so caution is particularly advised in cases of electrolyte abnormalities. Patients using diuretics or ACE inhibitors that may cause electrolyte abnormalities or those suspected of having hyponatremia should be managed carefully. It is necessary to check sodium, potassium, calcium, and kidney function through blood tests before and after colonic endoscopy. This medication should not be used in patients with intestinal obstruction, gastrointestinal obstruction, perforation, toxic colitis, or toxic megacolon, and should be administered with caution in patients with severe ulcerative colitis. The artificial sweetener aspartame included in this medication breaks down into phenylalanine and should not be given to patients with phenylketonuria. Patients allergic to this medication or its ingredients, suspected of having gastrointestinal obstruction or perforation, severe dehydration, or heart failure should not be treated. In particular, there is no clinical experience in children (under 18 years old), so it should not be used. Patients with intestinal stricture or severe constipation, the elderly, frail patients, patients at high risk of pulmonary aspiration due to vomiting reflex disorders or altered consciousness should be treated with caution. This medication can cause metabolic imbalances such as hunger, hypophosphatemia, hypokalemia, as well as gastrointestinal symptoms like sleep disturbances, dizziness, headaches, abdominal pain, nausea, and abdominal distension. Serious side effects such as allergic reactions, gastric mucosal damage in the elderly, cardiac arrest, and acute pulmonary edema have also been reported. Patients' bowel movements should be monitored before administration, and appropriate bowel movements should be observed during treatment. Intestinal activity begins about 1 hour after administration. If severe abdominal distension or pain occurs at this time, medication should be adjusted or stopped and medical consultation sought. If symptoms of fluid or electrolyte imbalance occur, blood tests should be performed to assess the condition and appropriate treatment should be initiated. For patients at high risk of cardiac disease or electrolyte imbalances, it is advisable to perform an electrocardiogram before and after administration. This medication may cause diarrhea, so adequate fluid intake is necessary. It is advisable not to use it with irritant laxatives as it may increase the risk of mucosal ulcers or ischemic colitis. Before administration, patients should eat lightly, and solid food should not be consumed 1 hour before administration. The effects of this medication on driving or operating machinery are unknown. When taken with other medications, it may affect absorption, so it is advisable to space out the timing of other drug intakes. Pregnant or breastfeeding women should use this medication with caution based on a physician's judgment as its safety has not been established. Caution is required for potential dehydration and electrolyte abnormalities due to overdose, and careful monitoring and appropriate treatment should be initiated if necessary. Prepared solutions should be consumed immediately, and any unused remaining solutions should be discarded within 24 hours, stored out of the reach of children.

Serious side effects

Hives, swelling, anaphylactic-like reactions, upper gastrointestinal bleeding due to gastric mucosal damage, esophageal perforation, cardiac arrest, acute pulmonary edema, palpitations, hypertension, arrhythmia, atrial fibrillation, peripheral edema, cardiac arrest, acute pulmonary edema, syncope, dehydration, anaphylaxis, swollen lips, swollen tongue, facial swelling, dyspnea, chest tightness, throat tightness, seizures, upper gastrointestinal bleeding due to Mallory-Weiss tear

Mild side effects

• Hunger
• hypophosphatemia
• hypokalemia
• sleep disturbances
• dizziness
• headache
• upper abdominal pain
• abdominal pain
• nausea
• abdominal bloating

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. It is important to maintain a storage temperature between 1 and 30 degrees Celsius to prolong the medication's efficacy.

Appearance

1) Preparation A: A white or yellowish powder in an aluminum foil pouch with a lemon flavor. 2) Preparation B: A white crystal or crystalline powder in an aluminum foil pouch that is odorless and sour tasting.

Package unit

Preparation A: 1 pouch (56.402g) x 4 pouches / carton, Preparation B: 1 pouch (5.3g) x 4 pouches / carton