Escular Capsule (Cefaclor Hydrate)

Adult dose

As Cefaclor Hydrate, take 250 mg per dose orally every 8 hours. In cases of severe infection (such as pneumonia) and infections with low sensitivity, the dose may be doubled. For acute gonococcal urethritis, this medication 3 g and probenecid 1 g should be administered in a single dose together.

Child dose

Administer 20 mg per kg of body weight divided every 8 hours. In cases of severe infection, otitis media, and infections with low sensitivity, a dose of 40 mg per kg of body weight may be used, with a maximum dose of

This medication works by binding to certain proteins and disrupting bacterial cell wall synthesis, leading to bacterial death. It should not be used in patients who have previously experienced severe allergic reactions or shock due to this medication or similar classes of antibiotics. Caution should be taken when using this drug in patients with a history of allergy to penicillin antibiotics or those with a family history of frequent allergic reactions such as bronchial asthma, rashes, and urticaria. Patients with severely reduced kidney function, those who cannot take oral medications, elderly patients, and those in poor general condition should be closely monitored for potential vitamin K deficiency. Caution is also required in patients with gastrointestinal diseases, particularly those with a history of colitis. This medication can rarely cause severe allergic reactions like shock or anaphylaxis, so patients should be closely observed during administration, and if any abnormal symptoms occur, the drug should be discontinued immediately, and appropriate measures should be taken. Severe reactions may occur on the skin; therefore, if symptoms such as rash, blisters, or skin peeling appear, administration should be stopped immediately. Regular blood tests are necessary as there may be a decrease in white blood cells or platelets, or the occurrence of anemia; if any abnormal findings are detected, administration should be stopped. Liver dysfunction or kidney dysfunction may arise; therefore, liver and kidney function tests should be regularly performed, and if abnormalities are found, administration should be ceased and treatment pursued. Severe colitis, such as pseudomembranous colitis, may rarely occur, so if there is severe abdominal pain or diarrhea, treatment should be discontinued immediately. If respiratory symptoms or symptoms of pneumonia develop, administration should cease and appropriate treatment should be received. Central nervous system symptoms such as anxiety, agitation, hallucinations, and dizziness may occur rarely, so caution is needed. Long-term use of this medication can lead to dysbiosis resulting in conditions like stomatitis or candidiasis. There may be a tendency to bleed due to vitamin K deficiency, so bleeding symptoms should be monitored. Caution is advised when used concomitantly with other drugs, particularly those affecting the kidneys or anticoagulants and oral contraceptives. Safety during pregnancy has not been established, and it should only be used if the benefits outweigh the risks. Caution should be exercised in nursing women as small amounts can be excreted in breast milk. It is advisable not to use this drug in neonates under 1 month of age as its safety and efficacy have not been confirmed. When administering to the elderly, adjustments should be made to the dose and administration intervals, and close observation is necessary as adverse reactions may occur more easily due to decreased bodily functions. This medication may affect the results of urine or blood tests, requiring careful interpretation of test results.

Serious side effects

Urticaria, severe swelling (edema), difficulty breathing, shock, anaphylactic symptoms, Stevens-Johnson syndrome, toxic epidermal necrolysis, liver abnormalities (including jaundice), reversible interstitial nephritis, acute kidney failure, severe colitis (pseudomembranous colitis), interstitial pneumonia, eosinophilic pulmonary infiltrates, sudden and very severe headache, seizures, confusion, visual disturbances, paralysis, severe edema or urination abnormalities (significant reduction in urine output, generalized severe edema,

Mild side effects

• General flushing
• vascular edema
• sensory disturbances
• fainting
• hypertension
• vasodilation
• rash
• itching
• fever
• lymphadenopathy

This medication should be stored in a tightly closed container that blocks light, and it is important to maintain a storage temperature between 1 and 30 degrees Celsius to preserve the effectiveness and prevent degradation.

Appearance

A hard capsule with a purple upper part and a white lower part filled with a white or yellowish crystalline powder.

Package unit

30 capsules/bottle, 300 capsules/bottle