Pediatric Agripal Pre-filled Syringe (Influenza Surface Antigen Vaccine)

Adult dosage

Administer the same dose as a single intramuscular injection once a year.

Children's dosage

For ages 6-35 months: administer 0.25 mL as a single intramuscular injection. However, infants and young children under 3 years who have not previously been infected with influenza or vaccinated should receive 2 doses spaced at least 4 weeks apart in the first year of vaccination.

This drug must have the health status of the vaccinee carefully checked before vaccination. In particular, it should not be administered to patients with fever, severe nutritional disorders, cardiovascular, renal, or liver disease in an acute phase or whose symptoms have worsened, acute respiratory illness, or active infectious disease. Furthermore, individuals with allergies to any components of this drug or those who have experienced severe allergic reactions from this drug in the past should avoid administration, as should those who have had adverse reactions following vaccination. Patients who have experienced convulsions within the past year or those who have had neurological disorders after receiving influenza vaccines should also be cautious. Patients with chronic cardiovascular, respiratory conditions, or diabetes may have worsening of their conditions due to influenza infection, so careful judgment is required during vaccination. This drug may cause side effects such as headache, sweating, muscle pain, joint pain, fever, malaise, chills, fatigue, and redness or swelling at the injection site, all of which typically resolve naturally within 1-2 days. Rarely, serious side effects such as thrombocytopenia, lymphadenopathy, allergic reactions, neurological abnormalities, and skin rashes may occur; any of these symptoms should prompt immediate consultation with medical staff. Acute allergic reactions like anaphylaxis may occur after vaccination, so medical staff should be prepared for rapid emergency response. This drug should not be injected intravascularly, and the injection site is recommended to be the lateral aspect of the upper arm, which should be disinfected before administration. On the day of vaccination and the following day, rest should be observed, and the injection site should be kept clean; if abnormal symptoms such as high fever or convulsions arise, the hospital should be visited immediately. Patients in an immunocompromised state may not exhibit adequate immune responses after this vaccination, requiring attention. In addition, different injection sites should be used for vaccinations combined with other vaccines, and immune response may be reduced in individuals receiving immunosuppressive therapy. This drug should be stored in a refrigerated environment (2-8°C), avoiding freezing and should be kept away from light. Before use, it should be brought to room temperature, shaken well to confirm it is in a clear liquid state, and it should not be used if discoloration or particulates are noted. Care should be taken as freezing may alter quality, and it is important to ensure the needle does not enter the vascular system. Unused medication should be disposed of properly according to relevant regulations.

Serious side effects

• Urticaria
• angioedema
• anaphylaxis
• severe thrombocytopenia
• neuritis
• encephalitis
• Guillain-Barre syndrome
• angioedema
• and vasculitis.

Mild side effects

Headache, sweating, muscle pain, joint pain, fever, malaise, chills, fatigue, redness at the injection site, swelling, pain, petechiae, induration, reactions similar to soft tissue reactions at the injection site, swelling at the injection site, pruritus, nonspecific rash, vasculitis, neuralgia, sensory disturbances, febrile convulsions, syncope, and presyncope.

This drug must be stored in a sealed container to prevent exposure to air and light. Additionally, the temperature should be maintained between 2 and 8 degrees Celsius and care should be taken to avoid freezing. Proper storage will help maintain the drug's efficacy and safety.

Appearance

Pre-filled syringe containing a clear liquid preparation

Package unit

10 pre-filled syringes/box [pre-filled syringe (0.25 mL)]