Aripiprazole Tablets 10 mg (Aripiprazole)

Adult dose

1. Schizophrenia - Recommended initial dose is 10 mg or 15 mg once daily, regardless of meals. - Can be adjusted within the range of 10-30 mg daily, and dose increases should not occur within 2 weeks. - Maintenance therapy: 15 mg once daily, reassessment required after 3 months of treatment. 2. Treatment of manic episodes or mixed episodes associated with bipolar disorder - Recommended initial dose of 15 mg once daily, can be increased up to 30 mg.

Child dose

1. Schizophrenia in adolescents (ages 13-17) - Recommended dose: 10 mg once daily, starting at 2 mg on day 1, increasing to 5 mg after 2 days, then to 10 mg after 2 more days. - Can be increased by 5 mg thereafter. -

This medication carries an increased risk of suicidal thoughts or behaviors when administered to children or adolescents, young adults with major depressive disorder or psychiatric illnesses, therefore the prescribing physician must carefully consider the risks and benefits before administration. Patients taking this medication should be closely monitored for worsening depression symptoms or the emergence of suicidal impulses and abnormal behavioral changes during the early treatment period, and family members or caregivers should also closely observe and report any abnormalities to the doctor immediately. When administering this medication to patients with bipolar disorder, mania symptoms or mixed episodes may occur, thus a risk assessment for bipolar disorder should be conducted beforehand. This medication can cause serious side effects known as neuroleptic malignant syndrome; if symptoms such as high fever, muscle rigidity, altered consciousness, or fluctuating blood pressure occur, immediate medical treatment is necessary. Long-term use may cause irreversible tardive dyskinesia, particularly in older patients, so it should be used at the lowest effective dose for the shortest duration necessary. In elderly patients with dementia, the risk of cerebrovascular events such as stroke and increased mortality may be elevated, hence this medication should not be used for patients with dementia-related psychiatric disorders. Patients with diabetes or at risk for diabetes should pay attention to blood sugar control, and if hyperglycemic symptoms occur, they should consult medical personnel immediately. This medication may cause orthostatic hypotension, so patients with unstable blood pressure or cardiovascular diseases need to be cautious during administration. Patients with a history of seizures or at high risk for seizures may experience exacerbation of seizures while taking this medication, hence caution should be exercised. This medication may cause drowsiness, dizziness, or impaired judgment, therefore caution is needed when driving or operating dangerous machinery. Thermoregulation ability may be impaired, so special care should be taken in conditions of excessive exercise, high temperatures, or dehydration. For patients with dysphagia, the risk of aspiration pneumonia should be carefully considered during use. This medication can cause hypersensitivity reactions, thus patients with a history of allergic reactions to this medication should not take it. While taking this medication, various side effects may appear such as nausea, vomiting, constipation, headache, insomnia, anxiety, extrapyramidal symptoms, drowsiness, fatigue, and changes in appetite; if any abnormal symptoms occur, patients should consult with medical personnel. Particularly in children and adolescents, side effects such as drowsiness, extrapyramidal symptoms, and tremors may occur more frequently. Regular physical exams, blood tests, and electrocardiograms should be conducted during the treatment, and attention should be paid to weight gain or changes in blood sugar levels. In case of overdose, immediate medical attention should be sought for appropriate treatment, and the medication should be started at the minimal effective dose as per the physician's directions.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urinary.

Mild side effects

• Nausea
• vomiting
• constipation
• headache
• dizziness
• akathisia
• anxiety
• insomnia
• restlessness
• orthostatic dizziness

This medication should be stored in a tightly closed container to protect it from air and moisture. The recommended storage temperature is at room temperature between 1 degree and 30 degrees.

Appearance

Pink rectangular tablets

Package unit

30 tablets/bottle, 100 tablets/bottle, (for export 30 tablets (10 tablets/PTP × 3))