Medication info
Dezaltan 16 mg (Candesartan Cilexetil)

Dezaltan 16 mg (Candesartan Cilexetil)

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›16mg / 1 tablet
Manufacturer / importer
한미약품(주)
Appearance
Light pink tablets that are convex on both sides with a line on one side.
Packaging
1 bottle/box [30 tablets/bottle], 1 bottle/box [300 tablets/bottle]
Approval status
Active

MFDS item code 201101757 · Approved 2011.03.29 · Insurance code 643505900

Summary

Main use
Treatment of essential hypertension and heart failure (left ventricular dysfunction)
Who takes it
Adults · Children
Adult dose
1. Essential Hypertension - The initial and maintenance doses of candesartan cilexetil are recommended to be administered orally at 8 to 16 mg once daily. - If blood pressure is not adequately controlled after 4 weeks at 16 mg once daily, the dose may be increased to a maximum of 32 mg once daily. - In patients with decreased effective blood volume and those with kidney disease, treatment should start with an initial dose of 4 mg. - In patients with liver disease, the initial dose should be 1.
Child dose
The safety and efficacy in children and adolescents under 18 have not been established.

Ingredients

Manufacturer
한미약품(주)

Efficacy & effects

Treatment of essential hypertension and heart failure (left ventricular dysfunction)

  • Essential hypertension
  • impaired left ventricular function
  • heart failure
View approved original text

This medication effectively lowers blood pressure in patients with essential hypertension, aiding in blood pressure management. It is also used in heart failure patients with impaired left ventricular function where ACE inhibitor treatment is not suitable or additional treatment is required. Particularly, it is appropriate for patients with heart failure classified in NYHA classes II to IV, and with a left ventricular ejection fraction of 40% or less. Therefore, this medication is effectively used for symptom improvement in patients with hypertension and certain types of heart failure.

How to take

Adult dose

1. Essential Hypertension - The initial and maintenance doses of candesartan cilexetil are recommended to be administered orally at 8 to 16 mg once daily. - If blood pressure is not adequately controlled after 4 weeks at 16 mg once daily, the dose may be increased to a maximum of 32 mg once daily. - In patients with decreased effective blood volume and those with kidney disease, treatment should start with an initial dose of 4 mg. - In patients with liver disease, the initial dose should be 1.

Child dose

The safety and efficacy in children and adolescents under 18 have not been established.

Precautions

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. People who are allergic to this drug or its ingredients, pregnant or nursing women, patients with severe liver dysfunction or cholestasis, and those with a history of hereditary angioedema should not take this medication. Additionally, patients with galactose intolerance or certain genetic metabolic disorders should also avoid this drug. Elderly patients, those with hyperkalemia, patients with mild to moderate liver dysfunction, certain heart valve disease patients, and patients with impaired kidney function should use this medication cautiously, monitoring their status closely before and during administration. Side effects such as dizziness, back pain, and respiratory infections may occur; rarely, serious side effects like blood abnormalities, liver dysfunction, muscle problems, and worsening kidney function may arise. Therefore, consultation with healthcare professionals is recommended upon the appearance of abnormal symptoms. In heart failure patients, hypotension or worsening kidney function may appear during use of this medication, so regular monitoring of serum potassium and creatinine levels is advised. This drug may enhance the blood pressure-lowering effects when used with other antihypertensives, so caution is necessary during co-administration. Particularly, when taken with potassium-sparing diuretics or potassium supplements, the blood potassium level may rise to dangerous levels, requiring attention. Patients preparing for surgery or anesthesia should stop taking this medication 24 hours before the procedure. In patients with poor kidney function or heart failure, the treatment should start at a low dose and gradually increase while observing the patient's condition closely. Caution is warranted when driving or operating machinery as dizziness or drowsiness may occur. Women who are pregnant or planning to become pregnant should avoid taking this medication, and nursing mothers should also refrain from use. The safety and efficacy of this drug have not been established in children and adolescents under 18. In cases of overdose, symptoms may include hypotension, dizziness, and rapid heartbeat; in emergencies, stabilizing the patient and providing necessary treatment is required. This medication should be kept out of reach of children and transferring it to other containers is not advised as it may compromise product quality.

Side effects and when to seek care immediately

Serious side effects

Hives, angioedema, severe edema, cold sweat, severe allergic reactions, fever associated with severe rash, blisters, skin peeling, pain in oral and ocular mucosa, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, jaundice (yellowing of skin or eyes), profound lethargy, liver dysfunction (jaundice), sudden and severe headaches, thunderclap headache, seizures,

Mild side effects

Dizziness, back pain, respiratory infections (upper respiratory infections, pharyngitis, rhinitis), fatigue, peripheral edema, chest pain, headache, bronchitis, cough, sinusitis, nausea, abdominal pain, diarrhea, vomiting, joint pain, proteinuria, weakness, fever, paresthesia, indigestion, gastroenteritis, tachycardia, palpitations, increased creatine kinase, hyperglycemia, hypertriglyceridemia, hyperuricemia, myalgia, nasal bleeding, anxiety, depression, drowsiness, dyspnea, rash, sweating

Not everyone experiences these, and they can vary from person to person.

Storage

This medication can be sensitive to air and moisture, so it must be stored in a tightly sealed container. It is recommended to maintain the storage temperature between 1 to 30 degrees Celsius. Proper storage ensures the effectiveness and safety of the medication over time.

Appearance and packaging

Appearance

Light pink tablets that are convex on both sides with a line on one side.

Package unit

1 bottle/box [30 tablets/bottle], 1 bottle/box [300 tablets/bottle]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.