Medication info
Olmesartan Plus Tablet 20/12.5 mg

Olmesartan Plus Tablet 20/12.5 mg

Prescription medicationTablet경구
Ingredient · strength
Olmesartan Medoxomil›20mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
(주)경보제약
Appearance
Yellowish round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201100985 · Approved 2011.02.25 · Insurance code 665001490

Summary

Main use
Treatment for essential hypertension blood pressure control
Who takes it
Adults · Children
Adult dose
In cases where blood pressure control is inadequate, administer 1 tablet once daily, irrespective of meals. The dosage should be adjusted every 2 to 4 weeks based on the patient's blood pressure response. Elderly patients should start at the lowest dose, and care should be taken to adjust the dose considering the patient's renal function, cardiac function, co-morbid conditions, and other medications.
Child dose
Safety and efficacy in pediatric patients have not been established.

Ingredients

Manufacturer
(주)경보제약

Efficacy & effects

Treatment for essential hypertension blood pressure control

  • Essential hypertension
View approved original text

Olmesartan Medoxomil and Hydrochlorothiazide are medications used for the treatment of essential hypertension. If blood pressure control is insufficient with monotherapy, these medications can be combined to effectively lower blood pressure. These drugs help relax blood vessels and promote sodium and fluid excretion, aiding in blood pressure control. Managing hypertension is crucial for preventing cardiovascular disease, so consistent use and regular blood pressure monitoring are necessary. This combination therapy contributes to improving patients' blood pressure and reducing the risk of complications.

How to take

Adult dose

In cases where blood pressure control is inadequate, administer 1 tablet once daily, irrespective of meals. The dosage should be adjusted every 2 to 4 weeks based on the patient's blood pressure response. Elderly patients should start at the lowest dose, and care should be taken to adjust the dose considering the patient's renal function, cardiac function, co-morbid conditions, and other medications.

Child dose

Safety and efficacy in pediatric patients have not been established.

Precautions

This medication can cause serious harm or death to the fetus and newborn if taken during the second and third trimesters of pregnancy; therefore, it should be discontinued immediately upon confirmation of pregnancy. It should not be administered to patients with known allergies to the components of this drug, those with certain kidney and liver diseases, pregnant or breastfeeding women, and patients with certain genetic metabolic disorders. Patients with low blood volume or sodium should be monitored closely when starting treatment as hypotension may occur initially. Use with caution in patients with impaired renal function, kidney transplant recipients, those with specific heart diseases, liver dysfunction, elderly individuals, and infants; regular blood tests to monitor renal function and electrolyte status should be performed if necessary. This medication can cause electrolyte imbalances, so if symptoms such as dry mouth, muscle cramps, or dizziness occur, medical consultation should be sought immediately. Blood pressure may drop significantly during treatment, so it is advisable to avoid high-altitude work or operating dangerous machinery. This medication may interact with various drugs; therefore, patients taking other medications must inform their healthcare provider, particularly when using potassium supplements, other antihypertensives, diuretics, lithium, or non-steroidal anti-inflammatory drugs. If breastfeeding, it is advisable to either stop breastfeeding or discontinue this medication as it may pass into breast milk and affect the infant. Safety and efficacy in pediatric patients have not yet been established, hence it is advisable not to use it in children. In case of overdose, symptoms such as hypotension, electrolyte imbalances, and dehydration may occur; appropriate treatment should be sought immediately. Rarely, side effects such as skin rash, headache, dizziness, gastrointestinal disturbances, blood abnormalities may occur; if symptoms persist or worsen, consult a healthcare provider.

Side effects and when to seek care immediately

Serious side effects

  • Hives, severe swelling (edema), chest tightness, difficulty breathing, angioedema, anaphylaxis, severe allergic reaction
  • Severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, severe skin adverse reactions
  • Respiratory issues: acute respiratory distress syndrome (ARDS), pulmonary edema, interstitial pneumonia, asthma attacks
  • Yellowing of skin or eyes (jaundice), hepatitis, acute cholecystitis, liver dysfunction, autoimmune issues

Mild side effects

  • Headache
  • dizziness
  • nausea
  • vomiting
  • diarrhea
  • indigestion
  • abdominal pain
  • fatigue
  • drowsiness
  • emotional blunting
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  • restlessness
  • palpitations
  • cough
  • upper respiratory infection
  • itching
  • rash
  • hematuria
  • peripheral edema
  • facial edema
  • chest pain
  • low back pain
  • increased blood pressure
  • nosebleed
  • arrhythmia
  • hair loss
  • drowsiness
  • skin rash

Not everyone experiences these, and they can vary from person to person.

Storage

Store this medication in a tightly closed container to protect it from air and moisture. The storage temperature should be suitable in a cool place between 1 and 25 degrees. This helps maintain the effectiveness of the medication for a longer period.

Appearance and packaging

Appearance

Yellowish round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.