Olmesartan Medoxomil Tablet 20 mg

Adult dose

The recommended initial dose is 10 mg once daily, taken regardless of meals. If blood pressure is not adequately controlled at this dose, it may be increased to 20 mg once daily. If additional blood pressure reduction is needed, the dose may be increased up to a maximum of 40 mg once daily. Blood pressure-lowering effects typically manifest within 2 weeks after starting treatment, with peak effects observed around 8 weeks. If blood pressure is still not controlled with monotherapy, combination therapy with thiazide diuretics such as Hydrochlorothiazide may be considered. To improve adherence, it is advisable to take the medication at the same time each day (e.g., in the morning) if possible. For patients at risk of intravascular volume depletion (e.g., those on diuretics, particularly renal impairment patients), treatment should be initiated at a lower dose, with close monitoring of their condition. <For the elderly> There is no need for dose adjustment when administering this medication to elderly patients aged 65 or older. No significant differences have been observed in the efficacy and safety between elderly and younger patients; however, more sensitive reactions cannot be excluded in some elderly individuals. <For patients with renal impairment> The maximum dose for patients with mild to moderate renal impairment (creatinine clearance 20-60 mL/min) is 20 mg once daily. <For patients with liver impairment> Patients with mild liver impairment do not require dose adjustment. For patients with moderate liver impairment, the recommended initial dose is 10 mg once daily, which may be increased up to a maximum of 20 mg daily. There is no experience using this medication in patients with severe liver impairment, so it is not recommended for such patients. <For children> The safety and efficacy in children have not been established.

Child dose

The safety and efficacy in children have not been established.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. Those allergic to any of the ingredients in this medication, pregnant or breastfeeding women, patients undergoing kidney dialysis, patients with severe liver impairment, patients with bile duct obstruction, and individuals with certain genetic lactose intolerance should not take this medication. Patients with reduced blood volume or low salt may experience hypotension, so their condition should be thoroughly checked before starting treatment. Patients with impaired kidney function or those who have received a kidney transplant should monitor their blood potassium levels and kidney function indicators regularly, and this medication is not recommended in cases of severe renal impairment. Since this medication lowers blood pressure, patients with aortic or heart valve disease should use it with caution, and if blood pressure drops too low, dizziness may occur, so care should be taken when performing hazardous tasks. During the course of this medication, side effects such as dizziness, headache, dyspepsia, and myalgia may occur, but most are mild and temporary. This medication may interact with other drugs, so it is advisable to consult with a doctor or pharmacist when taking potassium-sparing diuretics, potassium supplements, lithium, or nonsteroidal anti-inflammatory drugs together. Taking this medication during pregnancy can lead to serious problems such as decreased fetal kidney function, oligohydramnios, and cranial development retardation, so it should be discontinued immediately upon confirmation of pregnancy. Breastfeeding women should be cautious as this medication may be transmitted through breast milk, which could cause abnormal reactions in the baby, and it is advisable to stop breastfeeding or discontinue the medication. The safety and efficacy of this medication in children have not been established, so caution is necessary. Elderly patients may have increased plasma concentrations of this medication, so caution is needed during administration, and in the case of overdose, immediate medical attention is required due to symptoms such as hypotension or palpitations. This medication has been confirmed not to induce cancer even with long-term use; however, rare occurrences of liver dysfunction or allergic reactions may arise, so immediate consultation with medical staff is necessary if any abnormalities occur.

Serious side effects

• Hives, severe swelling (including angioedema and facial swelling), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions
• Severe rash accompanied by high fever, blisters, skin peeling, painful oral/ocular mucosa, severe skin adverse reactions
• Shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever
• Yellowing of the skin or eyes (jaundice), profound lethargy, liver dysfunction (jaundice)
• Sudden

Mild side effects

• Dizziness
• headache
• palpitations
• hypercholesterolemia
• hyperlipidemia
• hyperuricemia
• arthralgia
• arthritis
• myalgia
• rash

This medication should be stored in a sealed container to protect it from air and moisture, ideally at room temperature between 1 degree and 25 degrees Celsius. Proper storage will help maintain the medication's effectiveness and prevent deterioration.

Appearance

White, round, film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle