Olmesartan Medoxomil 20mg Tablets

Adult dose

The recommended initial dose is 10mg once daily, taken without regard to meals. If blood pressure is not adequately controlled, the dose may be increased to 20mg once daily. If additional blood pressure reduction is needed, the dose may be increased up to 40mg daily. The antihypertensive effects appear within 2 weeks after treatment initiation, with maximum effects observed around 8 weeks. If blood pressure is not adequately controlled with monotherapy, a thiazide diuretic such as hydrochlorothiazide may be added.

Child dose

Safety and efficacy for children have not been established.

This medication can cause serious harm or death to the fetus or newborn if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. People who are allergic to any ingredient in this medication, pregnant or nursing women, patients undergoing kidney dialysis, patients with severe liver impairment, patients with bile duct obstruction, and those with specific genetic lactose intolerance should not take this medication. Patients with decreased blood volume or low sodium levels may experience hypotension when starting this medication, so close monitoring of their condition is necessary. Patients with severe heart failure or reduced kidney function should regularly undergo blood tests as there may be changes in kidney function. Patients with kidney disease or kidney transplant recipients should periodically check serum potassium and creatinine levels while taking this medication, and it is not recommended for patients with severe kidney dysfunction. Patients with renal artery stenosis should carefully monitor changes in kidney function before using this medication long-term. This medication may cause hyperkalemia, so patients with heart failure or renal impairment should frequently check their potassium levels. Patients with aortic stenosis, mitral stenosis, obstructive, or hypertrophic cardiomyopathy should use this medication with special caution. Patients with primary aldosteronism may have reduced responsiveness to this medication; hence its use is not recommended. As this medication lowers blood pressure, it may cause dizziness, so caution should be exercised when operating dangerous machinery or driving. The antihypertensive effect of this medication may vary among different ethnic groups, so individual monitoring of effects and side effects is necessary. Mild side effects such as dizziness, headache, palpitations, dyspepsia, rash, etc., may occur, and rarely, angioedema or facial swelling can occur. If chronic diarrhea and weight loss persist, consult with a doctor to consider discontinuation of this medication. Combination with other antihypertensive agents or potassium-sparing diuretics may increase the risk of blood pressure lowering or hyperkalemia, so caution is advised. Avoid co-administration with lithium as it may increase lithium levels and result in toxicity. Caution is advised for use with non-steroidal anti-inflammatory drugs due to the risk of reduced kidney function; adequate hydration and regular kidney function tests are recommended. During pregnancy, this medication must be discontinued immediately to prevent serious anomalies in the fetus and newborn, and if nursing, consideration should be given to discontinuing either the medication or breastfeeding due to potential adverse effects on infants. Safety for children has not been established, so caution is needed for their use. Elderly patients may have altered drug metabolism, so blood pressure and kidney function should be monitored periodically during administration. In case of overdose, hypotension and palpitations may occur, and immediate treatment may be necessary. This medication has a very low risk of carcinogenicity or genotoxicity, and its safety has been confirmed even with long-term use.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), severe lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, urination issues

Mild side effects

• Dizziness
• headache
• palpitations
• abdominal pain
• dyspepsia
• gastroenteritis
• nausea
• hypercholesterolemia
• hyperlipidemia
• hyperuricemia

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 degree and 25 degrees Celsius.

Appearance

White, round film-coated tablet

Package unit

30 tablets/bottle