Olmesartan Plus Tablet 20/12.5 mg

Adult dose

This medication is administered once daily, one tablet, regardless of meals, after adjusting the dose of olmesartan medoxomil or hydrochlorothiazide alone if blood pressure is not adequately controlled. The dosage should be adjusted every 2-4 weeks according to the patient's blood pressure response. For patients taking high-dose hydrochlorothiazide monotherapy or those with fluid depletion and hyponatremia, the dose of olmesartan medoxomil should be reduced to 12.5 mg.

Child dose

Safety and efficacy in pediatric patients have not yet been established, so dosing guidelines are not recommended.

This medication can cause serious harm or death to the fetus and newborn if taken during the second and third trimesters of pregnancy; therefore, it should be discontinued immediately upon confirmation of pregnancy. Patients who are allergic to any of the ingredients in this medication or have specific kidney or liver diseases, as well as pregnant or nursing women, should not take this medication. Patients with low blood volume or salt depletion may experience hypotensive symptoms early in treatment and should be monitored closely. Patients with impaired kidney function or those who have received kidney transplants must regularly check kidney status and electrolyte levels through blood tests, and it is not recommended for patients with severe kidney impairment. The use of this medication is not recommended for patients with severe liver dysfunction, and caution is needed for patients with liver diseases. Patients with heart or vascular abnormalities, specific endocrine disorders, elderly patients, and infants require special caution when taking this medication. This medication may increase the risk of skin cancer, so patients should limit sun exposure and frequently monitor their skin condition during treatment. Symptoms such as dizziness, headache, indigestion, blood pressure changes, and electrolyte imbalances may occur during treatment, and if any abnormal symptoms appear, consult a doctor immediately. This medication may interact with other antihypertensive drugs, diuretics, potassium supplements, etc., so it is essential to inform the healthcare provider of any other medications being taken. Diabetic patients should regularly monitor their blood sugar levels, as this medication may affect blood sugar control and may require dosage adjustments if necessary. Dehydration or electrolyte imbalances may occur during treatment, so adequate fluid intake and regular blood tests are crucial. Women who are pregnant or nursing should avoid taking this medication or decide after consulting their physician. Safety and efficacy for children have not yet been established, so caution is needed for use. In case of an overdose, symptoms such as hypotension, electrolyte abnormalities, and dehydration may appear; immediate medical attention is required.

Serious side effects

Urticaria, severe swelling (edema), angioedema, anaphylactic reaction, severe hypotension, acute renal failure, acute respiratory distress syndrome (ARDS), liver abnormalities (jaundice), severe skin adverse reactions (severe rash, blisters, skin peeling, pain in oral/ocular mucosa), neurological symptoms (severe headache, seizures, consciousness disturbance, visual disturbances, paralysis), hyponatremia, hypokalemia, acute angle-closure glaucoma, choroidal effusion, hepatitis, interstitial nephritis

Mild side effects

• Nausea
• vomiting
• dizziness
• headache
• diarrhea
• abdominal pain
• indigestion
• gastritis
• cough
• itching

This medication should be stored in a tightly closed container to protect it from air and moisture and is best kept at room temperature between 1°C and 25°C. This storage method helps maintain the effectiveness of the drug for a longer period.

Appearance

Round film-coated tablet with a light yellow-orange color

Package unit

30 tablets/bottle, 300 tablets/bottle