Medication info
Candesartan Plus Tablet 16/12.5mg

Candesartan Plus Tablet 16/12.5mg

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›16mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
영진약품(주)
Appearance
Pale orange oval tablet with a score line on one side
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201100879 · Notified 2011.02.23 · Insurance code 642403180

Summary

Main use
Improvement of essential hypertension
Who takes it
Adults
Adult dose
The recommended dosage for this medication is one tablet daily, taken regardless of meals. For adults, it is important to adjust the dose of Candesartan Cilexetil before switching to this medication. Direct conversion from monotherapy may be considered when clinically appropriate. Antihypertensive effects are typically achieved within four weeks of starting treatment. No dose adjustment is needed for the elderly. Patients with decreased intravascular effective blood volume and renal impairment should be monitored carefully regarding their Candesartan Cilexetil dosage.

Ingredients

Manufacturer
영진약품(주)

Efficacy & effects

Improvement of essential hypertension

  • Essential hypertension
View approved original text

Essential hypertension may not be adequately controlled by monotherapy with individual components alone. In such cases, it is important to utilize combination therapy or other treatments to manage blood pressure. This medication is used to effectively control essential hypertension and improve elevated blood pressure.

How to take

Adult dose

The recommended dosage for this medication is one tablet daily, taken regardless of meals. For adults, it is important to adjust the dose of Candesartan Cilexetil before switching to this medication. Direct conversion from monotherapy may be considered when clinically appropriate. Antihypertensive effects are typically achieved within four weeks of starting treatment. No dose adjustment is needed for the elderly. Patients with decreased intravascular effective blood volume and renal impairment should be monitored carefully regarding their Candesartan Cilexetil dosage.

Precautions

This medication can cause serious harm to the fetus and newborn, especially during the second and third trimesters of pregnancy. Therefore, if pregnancy is confirmed, it should be discontinued immediately. Individuals allergic to this medication or sulfonamide derivatives, women who are pregnant or planning to become pregnant, and those with severe kidney or liver dysfunction should not take this medication. Patients with a history of angioedema, gout, primary hyperaldosteronism, hyponatremia, hypokalemia, hypercalcemia, Addison's disease, etc., should also avoid using this medication. Patients with reduced blood volume, those at risk of hepatic coma, patients with cardiac valve disease, and those with hyperkalemia should use this medication cautiously. This medication lowers blood pressure, so elderly individuals, patients with cardiovascular disease, and those with kidney disease should use it with caution, and regular blood pressure and blood tests should be conducted to monitor their condition. The hydrochlorothiazide component can cause electrolyte imbalances, necessitating periodic testing of potassium, sodium, calcium, and other levels; special caution is required for those at risk of hypokalemia or hyperkalemia. If unusual symptoms such as sudden dizziness, headache, skin rash, or difficulty breathing occur during the course of this medication, the patient should consult a healthcare provider immediately. This medication may interact with other antihypertensive drugs, diuretics, and potassium supplements, so inform your doctor or pharmacist of any other medications you are taking. Pregnant or nursing women should not take this medication, and nursing mothers are advised to discontinue breastfeeding while taking it. This medication has not been established as safe and effective for use in children and adolescents, so it is best not to use it in this population. In case of overdose, symptoms such as hypotension, dizziness, and vomiting may occur, and immediate medical attention should be sought.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), angioedema, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mouth/eye mucosa, severe skin reactions, severe allergic reactions, difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, jaundice, profound lethargy, liver abnormalities, sudden and very severe headache, thunderclap headache, seizures, confusion, visual disturbances

Mild side effects

  • Headache
  • back pain
  • dizziness
  • respiratory infections
  • symptoms similar to those of the flu
  • sinusitis
  • bronchitis
  • urinary tract infection
  • nausea
  • bruising
Show 18 more
  • tachycardia
  • fatigue
  • abdominal pain
  • pharyngitis
  • dyslipidemia
  • nasopharyngitis
  • cough
  • increased blood sugar
  • elevated serum uric acid
  • increased ALT (SGPT)
  • increased AST (SGOT)
  • increased creatinine
  • increased urea
  • increased potassium
  • decreased sodium
  • leukopenia
  • neutropenia
  • agranulocytosis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent air or moisture from entering and is best kept in a cool place below 30 degrees Celsius. Proper storage maintains the medication's effectiveness and prevents deterioration.

Appearance and packaging

Appearance

Pale orange oval tablet with a score line on one side

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.