Medication info
Candesartan Tablets 8 mg (Candesartan Cilexetil)

Candesartan Tablets 8 mg (Candesartan Cilexetil)

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›8mg / 1 tablet
Manufacturer / importer
일동제약(주)
Appearance
White tablets that are round and convex on both sides
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201100299 · Approved 2011.01.20 · Insurance code 642904200

Summary

Main use
Improvement of essential hypertension and heart failure (left ventricular dysfunction)
Who takes it
Adults · Children
Adult dose
Essential hypertension: The recommended starting and maintenance dose for adults is oral administration of 8 to 16 mg of Candesartan Cilexetil once daily. If blood pressure is not adequately controlled after 4 weeks at 16 mg once daily, the dose may be increased up to 32 mg once daily.Max 32 mg if still poorly controlled. No initial dose adjustment is required for elderly patients. For patients with diminished effective blood volume: starting dose of 4 mg. For patients with renal impairment: starting dose of 4 mg.
Child dose
Safety and efficacy for children and adolescents under 18 have not been established.

Ingredients

Manufacturer
일동제약(주)

Efficacy & effects

Improvement of essential hypertension and heart failure (left ventricular dysfunction)

  • Essential hypertension
  • heart failure
  • left ventricular contraction dysfunction
  • reduced left ventricular ejection fraction
View approved original text

This medication helps to stabilize blood pressure in patients with essential hypertension, preventing cardiovascular complications. It can also be used in heart failure patients with reduced left ventricular contraction function, and is especially effective in cases where additional therapy beyond ACE inhibitors is needed or where ACE inhibitor tolerance is poor. By improving blood circulation and reducing the burden on the heart, it contributes to the overall improvement of heart function. Therefore, it is useful for the treatment of essential hypertension and certain heart failure patients.

How to take

Adult dose

Essential hypertension: The recommended starting and maintenance dose for adults is oral administration of 8 to 16 mg of Candesartan Cilexetil once daily. If blood pressure is not adequately controlled after 4 weeks at 16 mg once daily, the dose may be increased up to 32 mg once daily.Max 32 mg if still poorly controlled. No initial dose adjustment is required for elderly patients. For patients with diminished effective blood volume: starting dose of 4 mg. For patients with renal impairment: starting dose of 4 mg.

Child dose

Safety and efficacy for children and adolescents under 18 have not been established.

Precautions

This drug may cause serious harm or death to the fetus and newborn when administered to pregnant women, so the use should be discontinued immediately upon confirmation of pregnancy. Those who are allergic to this drug or its components, pregnant women or women of childbearing potential, nursing mothers, patients with severe liver impairment, patients with a history of angioedema, and individuals with certain genetic disorders should avoid taking this drug. Elderly patients, patients with hyperkalemia, liver disease, heart diseases, and those with impaired kidney function should use this drug cautiously and require regular blood tests and condition monitoring. This drug may cause side effects such as dizziness, back pain, and respiratory infections, and in rare cases, serious adverse reactions may occur. Therefore, if any abnormal symptoms arise, medical consultation should be sought immediately. In heart failure patients, hypotension, hyperkalemia, and renal function impairment may occur, making regular checks of blood potassium levels and kidney function important. When taken with other antihypertensive agents, the blood pressure-lowering effect may be increased; thus, caution is needed during administration. Particularly, when used in combination with potassium-sparing diuretics or potassium supplements, blood potassium levels may become dangerously elevated. Pregnant women or women planning to become pregnant should not take this medication, and nursing mothers should also ideally discontinue breastfeeding or avoid taking this medication. Safety and efficacy for children and adolescents under 18 years have not been established, so its use in this population is not recommended. Elderly patients may experience serious adverse effects, such as cerebral infarction, due to excessive blood pressure lowering, so careful monitoring is advised during administration. In cases of overdose, symptoms such as hypotension, dizziness, and tachycardia may appear, necessitating immediate visit to a medical institution for proper treatment, and this drug is not removed by dialysis. Keep out of reach of children, and avoid transferring to other containers as it may compromise product quality.

Side effects and when to seek care immediately

Serious side effects

Urticaria, angioedema (swelling of the face, lips, tongue, throat, etc.), cold sweat, high fever, severe rash, blisters, peeling skin, pain in oral/eye mucosa, difficulty breathing or shortness of breath, asthma attacks, cough with fever indicating respiratory issues, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, significantly reduced urine output

Mild side effects

Dizziness, back pain, respiratory infections (upper respiratory infections, pharyngitis, rhinitis), fatigue, peripheral edema, chest pain, headache, bronchitis, cough, sinusitis, nausea, abdominal pain, diarrhea, vomiting, arthralgia, proteinuria, weakness, fever, paresthesia, dyspepsia, gastritis, tachycardia, palpitations, increased creatine kinase, hyperglycemia, hypertriglyceridemia, hyperuricemia, myalgia, epistaxis, anxiety, depression, drowsiness, shortness of breath, rash, sweating

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air and moisture, so it must be stored in a tightly sealed container. Additionally, it is best to store the medication at room temperature between 1 and 30 degrees Celsius, avoiding excessively cold or hot conditions. This storage method preserves the medication's effectiveness.

Appearance and packaging

Appearance

White tablets that are round and convex on both sides

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.