Medication info
Candesartan Cilexetil Tablet 16 mg

Candesartan Cilexetil Tablet 16 mg

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›16mg / 1 tablet
Manufacturer / importer
영진약품(주)
Appearance
Light yellow-pink tablet with a biconvex round shape on both sides
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201100216 · Approved 2011.01.14 · Insurance code 642403170

Summary

Main use
Improvement of essential hypertension and heart failure (left ventricular dysfunction)
Who takes it
Adults · Children
Adult dose
For adults with essential hypertension: The recommended initial and maintenance dosage is 8 to 16 mg of Candesartan Cilexetil taken orally once daily. If blood pressure is not adequately controlled after 4 weeks at 16 mg once daily, the dose may be increased to a maximum of 32 mg once daily. For adults with heart failure: The initial dose is recommended to be 4 mg taken orally once daily. The dosage may be doubled at intervals of at least 2 weeks.
Child dose
Safety and efficacy for adolescents and children under 18 years have not been established.

Ingredients

Manufacturer
영진약품(주)

Efficacy & effects

Improvement of essential hypertension and heart failure (left ventricular dysfunction)

  • Essential hypertension
  • heart failure
  • left ventricular systolic dysfunction
  • reduced left ventricular ejection fraction
View approved original text

This medication is used to control blood pressure in patients with essential hypertension. It also helps in the treatment of heart failure symptoms in patients whose left ventricular systolic function is compromised, where additional treatment with ACE inhibitors is needed or not well tolerated. This medication contributes to alleviating the patient’s symptoms and improving the quality of life through the improvement of heart function and blood pressure control.

How to take

Adult dose

For adults with essential hypertension: The recommended initial and maintenance dosage is 8 to 16 mg of Candesartan Cilexetil taken orally once daily. If blood pressure is not adequately controlled after 4 weeks at 16 mg once daily, the dose may be increased to a maximum of 32 mg once daily. For adults with heart failure: The initial dose is recommended to be 4 mg taken orally once daily. The dosage may be doubled at intervals of at least 2 weeks.

Child dose

Safety and efficacy for adolescents and children under 18 years have not been established.

Precautions

This medication can cause serious harm to the fetus if taken during pregnancy, especially in the second and third trimesters; therefore, it should be discontinued immediately upon confirmation of pregnancy. This medication should not be used by individuals who are allergic to this drug or its components, pregnant or potentially pregnant women, nursing mothers, individuals with severe liver dysfunction, those with a history of hereditary angioedema, and patients with primary hyperaldosteronism. Caution should be exercised when using this medication in elderly patients, patients with hyperkalemia, patients with mildly impaired liver function, patients with heart valve disease or ischemic heart disease, and patients with kidney disease; it is particularly important to regularly monitor kidney function and blood potassium levels in these individuals. While taking this medication, side effects such as dizziness, back pain, and respiratory infections may occur, and some patients may experience serious adverse reactions like hypotension, worsening kidney function, or hyperkalemia, thus it is essential to consult with healthcare professionals immediately if such symptoms occur. In heart failure patients or recipients of kidney transplants and blood dialysis patients, blood pressure and kidney function should be monitored more carefully when using this medication, and caution should be exercised regarding interactions when used in combination with other antihypertensives. This medication can cause dangerously high blood potassium levels when taken with certain diuretics or potassium supplements; thus, patients should have blood tests frequently according to their doctor’s instructions when used in combination. Women who are pregnant or breastfeeding are advised not to take this medication, and if it must be taken, breastfeeding should be discontinued. Safety for adolescents and children under 18 years of age has not been established, and use is not recommended. Elderly patients should be cautious while taking this medication as excessive hypotension can increase the risk of stroke, among other complications. In cases of overdose, symptoms such as hypotension, dizziness, and rapid heartbeat may arise; if this occurs, patients should go to a hospital immediately for appropriate treatment. This medication should be kept out of reach of children and should not be transferred into another container for safety. Caution is needed as dizziness may occur while driving or operating machinery.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), angioedema (swelling of the face, lips, tongue, throat), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, difficulty breathing, asthmatic attacks, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), severe lethargy, sudden and very severe headache, lightning-like pain

Mild side effects

Dizziness, back pain, respiratory infections (upper respiratory infections, pharyngitis, rhinitis), fatigue, peripheral edema, chest pain, headache, bronchitis, cough, sinusitis, nausea, abdominal pain, diarrhea, vomiting, joint pain, proteinuria, weakness, fever, sensory abnormalities, indigestion, gastroenteritis, tachycardia, palpitations, increased creatine kinase, hyperglycemia, hypertriglyceridemia, hyperuricemia, myalgia, epistaxis, anxiety, depression, drowsiness, rash, increased sweating, hematuria,

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture exposure. It is best to maintain storage temperatures between 1 and 30 degrees Celsius at room temperature.

Appearance and packaging

Appearance

Light yellow-pink tablet with a biconvex round shape on both sides

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.