Aitorin Tablet 10/20

Adult dose

This medication is administered once daily in the evening, regardless of meals. The dosage range for patients with primary hypercholesterolemia is 10/10mg to 10/40mg per day, with the generally recommended initial dose being 10/20mg. Patients with a lesser need for LDL cholesterol reduction may start at 10/10mg per day. For patients with homozygous familial hypercholesterolemia, the recommended dose is 10/40mg per day, taken once daily in the evening.

This medication can cause serious muscle-related side effects such as myopathy and rhabdomyolysis, so if muscle pain or weakness occurs during treatment, medical consultation should be sought immediately. The risk of myopathy and rhabdomyolysis may increase especially when this medication is taken at high doses or in conjunction with certain other drugs. This medication should not be administered to patients with hypersensitivity to the ingredients or those with liver dysfunction, as well as to women who are pregnant or breastfeeding. Moreover, it should not be used in combination with strong CYP3A4 inhibitors or certain drugs like gemfibrozil, cyclosporine, and danazol, and attention must be paid to drug interactions. Since this medication may affect liver function, it should be used cautiously in patients with a history of liver disease or abnormal liver function test results. Elderly patients or those at risk of diabetes should be monitored regularly for blood glucose and liver function during treatment. If unexplained muscle pain, tenderness, or weakness occurs, or if symptoms of liver dysfunction appear, immediate medical attention is required. This medication should not be prescribed to women planning to become pregnant; if pregnancy is confirmed, treatment should be stopped immediately. For breastfeeding mothers, it is safer to discontinue breastfeeding while taking this medication. Caution is advised for use in children and adolescents, as safety and efficacy have not been sufficiently confirmed. During treatment with this medication, grapefruit juice and certain other drugs should be avoided, and consulting with healthcare providers before and after medication is essential.

Serious side effects

• Hives
• angioedema
• anaphylaxis
• severe swelling
• chest tightness
• difficulty breathing
• skin peeling
• blisters
• severe rashes with fever
• oral/ocular mucosal pain

Mild side effects

• Headache
• diarrhea
• influenza
• upper respiratory tract infection
• muscle pain
• limb pain
• fatigue
• abdominal pain
• nausea
• constipation

This medication is sensitive to air and moisture; therefore, it must be stored in a tight container with the lid securely closed when not in use. Additionally, it should be stored at room temperature between 1°C and 30°C, avoiding extremes of temperature.

Appearance

White to off-white, bi-convex, rectangular tablet

Package unit

Domestic: 30 tablets (10 tablets/PTP x 3), Export: 30 tablets (10 tablets/PTP x 3)