Sevikar 5/40 mg

Adult dose

Take one tablet daily with water, regardless of meals. It is preferable to take it at the same time daily (e.g., morning). The maximum dosage is 10/40 mg. The peak blood pressure-lowering effect occurs within two weeks of administration, so doses should be adjusted at intervals of more than two weeks based on blood pressure response. Recommended dosages are as follows: - 5/20 mg: for patients inadequately controlled with amlodipine 5 mg.

Child dose

Safety and efficacy have not been established for pediatric patients under the age of 18.

This medicine can cause serious damage to the fetus and newborn during the second and third trimesters of pregnancy, so treatment should be discontinued immediately upon confirmation of pregnancy. This medication should not be administered to individuals allergic to its active ingredients or similar components, pregnant or breastfeeding women, patients with severe liver dysfunction, severe aortic stenosis, biliary obstruction, patients on dialysis, those in a state of shock, and certain patients with diabetes or severely impaired kidney function. Patients with low blood pressure due to fluid or salt deficiency may experience hypotensive symptoms, so close monitoring is required initially, and appropriate action should be taken if hypotension occurs. As vasodilation can lead to hypotension, caution is advised for certain heart disease patients like those with aortic stenosis. Patients with heart failure should be carefully monitored, and those with impaired kidney function may experience kidney damage; close monitoring of their condition is required. Patients with decreased liver function should be cautious as the metabolism of this medicine may slow down. During treatment, side effects such as dizziness, headache, hypotension, edema, dyspepsia, skin rash may occur; therefore, any unusual symptoms should be discussed with healthcare professionals. This medicine may interact with other medications; you must inform your healthcare provider about any other medications you're taking, especially to avoid concurrent use with grapefruit juice. This medication should not be used during pregnancy, and those planning to become pregnant or already pregnant must consult a doctor. If breastfeeding, it's important to either discontinue nursing or stop taking the medication since it can transfer into breast milk and affect the infant. Safety and efficacy have not been established for children under the age of 18, so it is not recommended for that age group. Elderly patients may require dosage adjustments due to decreased kidney and liver function affecting the medication's effectiveness. In cases of overdose, severe hypotension, vasodilation, and tachycardia can occur, requiring immediate medical attention.

Serious side effects

Hives, severe swelling (edema), difficulty breathing, hypotension, angioedema, liver abnormalities (jaundice), toxic epidermal necrolysis, acute kidney failure, increased serum creatinine, exacerbation of cerebral infarction, severe edema associated with increased blood pressure, severe allergic reactions, severe skin adverse reactions, serious neurological symptoms.

Mild side effects

• Dizziness
• headache
• drowsiness
• altered sensation
• decreased libido
• palpitations
• nausea
• vomiting
• dyspepsia
• diarrhea

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is recommended to maintain storage temperatures between 1 to 30 degrees Celsius.

Appearance

Pale yellow, round, film-coated tablet

Package unit

28 tablets (14 tablets/PTP X 2)/carton