Cresnon 5 mg (Rosuvastatin Calcium)

Adult dose

This medication can be taken at any time of the day, regardless of meals. The initial dose is 5 mg once daily, and if a greater reduction in LDL cholesterol is needed, it can be adjusted to a maintenance dose. The maintenance dose is generally 10 mg once daily, and most patients will be managed at this dose. Further adjustments to the maintenance dose should be made at intervals of 4 weeks or more based on LDL cholesterol levels, therapeutic goals, and patient response.

Child dose

The usual dosage range is 5 mg to 20 mg once daily. The administration dose should be individually adjusted according to the recommended treatment goals for each patient. The dosage should be adjusted at intervals of 4 weeks or more.

This medication should not be administered to certain patients, such as those with allergies to its components, severe liver dysfunction, muscle disorders, those taking certain immunosuppressants, individuals with severely impaired kidney function, women who are pregnant or breastfeeding, and those with genetic issues like lactose intolerance. Additionally, this medication can affect muscles and may cause muscle pain or myopathy symptoms, so those with muscle problems or at high risk for muscle-related diseases should exercise particular caution. If such symptoms occur, the patient must inform healthcare personnel immediately, and in some cases, discontinuation may be necessary. Regular liver function tests should be conducted, and those with a history of liver disease or excessive alcohol consumption should be especially careful. This medication may raise blood sugar levels, so individuals at risk for diabetes should manage their blood sugar diligently. It can interact with various other medications, so if the patient is taking any medications, they must inform their healthcare providers. When taken with certain drugs, the blood concentration of this medication may increase, raising the risk for muscle-related side effects. Women of childbearing potential should use appropriate contraception, and pregnant women should not take this medication. It's also advisable for breastfeeding women to avoid this medication. There is no specific antidote in case of overdose, so treatment should be symptomatic, and liver function and muscle enzyme tests are necessary. Lastly, this medication can cause dizziness; therefore, caution is needed when driving or operating machinery. Patients experiencing any abnormal symptoms or discomfort while taking this medication should consult their healthcare provider immediately.

Serious side effects

Allergic reactions including urticaria and angioedema, chest tightness, difficulty breathing, respiratory distress, severe muscle weakness, ophthalmoplegia, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, acute renal failure, oliguria, severe edema, severe skin reactions, rhabdomyolysis, immune-mediated necrotizing myopathy, liver failure, severe allergic reactions, severe neurological reactions

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• pruritus
• myalgia
• asthenia
• diarrhea
• hematuria

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is advisable to maintain room temperature between 1 and 30 degrees Celsius to preserve the medication's effectiveness over time.

Appearance

Yellow round film-coated tablets

Package unit

300 tablets/bottle, 30 tablets/PTP