Medication info

Neocap Injection (Caffeine Citrate)

Prescription medication
Ingredient · strength
Anhydrous Caffeine›10mg / 1mLCitric Acid Hydrate›5mg / 1mLSodium Citrate Hydrate›8.3mg / 1mL
Manufacturer / importer
(주)한국팜비오
Appearance
Brown vial containing a colorless transparent injection solution
Packaging
10 vials/box [(1mL/vial x 10)]
Approval status
Active

MFDS item code 201003574 · Approved 2010.05.18 · Insurance code 659900440,659900530

Summary

Main use
Improvement of apnea in premature infants
Who uses it
Adults · Children
Adult dosage
Initial dose: 1mL/kg administered intravenously using a syringe pump for more than 30 minutes (injection). Maintenance dose: 0.25mL/kg once daily administered orally (oral solution) or intravenously using a syringe pump for more than 10 minutes (injection).
Children's dosage
Initial dose: 1mL/kg (Caffeine Citrate 20mg/kg) administered intravenously using a syringe pump for more than 30 minutes (injection). Maintenance dose: 0.25mL/kg (Caffeine Citrate

Ingredients

Manufacturer
(주)한국팜비오

Efficacy & effects

Improvement of apnea in premature infants

  • Apnea in premature infants
View approved original text

Apnea in premature infants refers to a condition where newborns do not breathe normally. Special medications or medical devices are used for this treatment, focusing on stabilizing breathing. The pharmacist can explain that this medication helps support the respiratory function of premature infants, alleviating apnea symptoms and inducing healthy respiratory patterns. This treatment can protect the baby's life, positively influence growth, and effectively improve apnea symptoms.

Dosage and Administration

Adult dosage

Initial dose: 1mL/kg administered intravenously using a syringe pump for more than 30 minutes (injection). Maintenance dose: 0.25mL/kg once daily administered orally (oral solution) or intravenously using a syringe pump for more than 10 minutes (injection).

Children's dosage

Initial dose: 1mL/kg (Caffeine Citrate 20mg/kg) administered intravenously using a syringe pump for more than 30 minutes (injection). Maintenance dose: 0.25mL/kg (Caffeine Citrate

Precautions

This medication can cause a serious intestinal disease known as necrotizing enterocolitis when used in newborns, so symptoms of this condition should be closely monitored during administration. This medication should not be used in patients with an allergy to any of its components. Caution should be exercised in patients with convulsive disorders or problems with the heart, liver, and kidneys, and consultation with a specialist should be sought if necessary. Various adverse reactions may occur during administration, including skin rashes, respiratory distress, vascular coagulation issues, and impaired kidney function. This medication stimulates the central nervous system, and overdose can lead to seizures; therefore, patients with convulsive disorders should be particularly cautious. Interactions with other medications may occur, especially those that affect the enzymes that break down this medication in the liver, necessitating dosage adjustments. There is insufficient research on its use during pregnancy, so pregnant women should consult their doctor before using this medication. Symptoms of overdose may include fever, tremors, vomiting, hyperglycemia, and seizures; in such cases, immediate medical assistance is required. This medication is for single use only; remaining medication should be discarded, and the solution should be checked for abnormalities before administration. Store in a sealed container to prevent contact with air, and keep it in a cool place between 15 and 30 degrees Celsius. This will help maintain the medication's efficacy for a longer period.

Side effects and when to seek care immediately

Serious side effects

  • Necrotizing enterocolitis
  • death
  • bleeding
  • disseminated intravascular coagulation
  • intracranial hemorrhage
  • respiratory distress
  • pulmonary edema
  • renal failure
  • seizures

Mild side effects

Accidental injury, anorexia, sepsis, gastritis, gastrointestinal bleeding, acidosis, abnormal healing, dry skin, rash, skin rupture, retinopathy in premature infants, central nervous system excitation (sensitivity, anxiety, irritability), tachycardia, increased left ventricular output, increased cardiac output, increased gastric aspiration, gastrointestinal intolerance, hypoglycemia, hyperglycemia, increased urination, increased creatinine clearance, increased excretion of sodium and calcium, fever, rapid breathing, tremors,

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to prevent contact with air and kept in a cool place between 15 and 30 degrees Celsius. Proper storage helps maintain the medication's efficacy over time.

Appearance and packaging

Appearance

Brown vial containing a colorless transparent injection solution

Package unit

10 vials/box [(1mL/vial x 10)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.