Hepcure Tablet 10 mg (Adefovir Dipivoxil)

Adult dose

Adults: The recommended dose of adefovir dipivoxil is 10 mg orally once daily, with or without food. Patients with renal impairment: In patients with a creatinine clearance of less than 50 mL/min, adjust the dosing interval as shown in the table below. The pharmacokinetics of adefovir have not been evaluated in patients with a creatinine clearance of less than 10 mL/min who are not receiving hemodialysis; therefore, no dosing recommendations are available for these patients.

This medication must be taken at the recommended dosage and should not be exceeded. After stopping treatment, hepatitis may worsen, so liver function should be regularly monitored for a period after discontinuing the medication. Particularly, patients with compromised liver function or advanced cirrhosis should be carefully monitored for liver condition from the beginning of treatment. This medicine can affect the kidneys, so patients with impaired kidney function or those taking medications that may burden the kidneys should frequently check kidney function. Kidney function should be monitored through blood tests, and dosage adjustments may be necessary if needed. HIV infection status must be confirmed, and patients infected with HIV should use this medication in conjunction with appropriate antiviral therapy, not alone. Rarely, severe side effects such as lactic acidosis or hepatomegaly may occur, necessitating immediate consultation with healthcare professionals if unusual symptoms appear. During the use of this medication, care is needed to prevent the transmission of hepatitis B, and caution should be exercised to avoid infecting others. Women who are pregnant or may become pregnant must consult a specialist before taking this medication and should implement effective contraception if necessary. The safety and efficacy of this medication have not been established in children or adolescents and should be used cautiously in this population. Elderly patients are at higher risk for reduced kidney function, so care should be taken when administering the drug. In case of overdose, immediate medical attention is required, and blood dialysis can remove some of this medication. This medication should be kept out of reach of children and should not be transferred to other containers. Additionally, when taken with other medications that may affect kidney function, close monitoring for side effects is necessary.

• Worsening of hepatitis
• elevated serum ALT
• weakness
• headache
• fever
• abdominal pain
• nausea
• vomiting
• pneumatosis intestinalis
• diarrhea

This medication should be stored in a tightly sealed container to prevent air and moisture from entering. A storage temperature between 1 degree and 30 degrees Celsius at room temperature is recommended to maintain the drug's efficacy and safety for a long time.

Appearance

White to grayish-white round tablet

Package unit

30 tablets/bottle