JW Donapezil Orally Disintegrating Tablets 10 mg

Adult dose

As Donepezil Hydrochloride, administer 5 mg once daily before sleep. After administering 5 mg for 4 to 6 weeks, evaluate the clinical response to possibly increase to 10 mg. The maximum daily dosage is 10 mg. The orally disintegrating tablet can be placed on the tongue to dissolve and taken with water or can be taken without water.

Child dose

There is no experience in using this medicine in pediatric patients.

This medicine contains the ingredient Donepezil Hydrochloride and is primarily used to treat symptoms of Alzheimer's type dementia. This medicine should not be administered to individuals who are allergic to Donepezil Hydrochloride, piperidine derivatives, or any other components of this medicine. It is safest to avoid using this medicine during pregnancy or in women who may become pregnant, as well as in breastfeeding women. Patients with cardiac diseases, especially those with bradycardia or heart conduction disorders, should use this medicine with caution, as it may lead to bradycardia or arrhythmia. Patients taking non-steroidal anti-inflammatory drugs or with a history of peptic ulcers should be cautious, as increased gastric acid secretion and enhanced gastrointestinal motility may exacerbate ulcers. Patients with asthma or obstructive pulmonary diseases may experience worsening symptoms due to bronchoconstriction and increased mucus secretion, thus careful monitoring is necessary. Patients with extrapyramidal disorders such as Parkinson's disease should use this medicine cautiously due to its cholinergic effects, which may worsen their symptoms. During treatment, there may be heart-related adverse reactions such as syncope, bradycardia, heart block, or QT interval prolongation; immediate consultation with a healthcare professional is necessary if these symptoms occur. Gastrointestinal adverse reactions including peptic ulcers, gastrointestinal bleeding, nausea, vomiting, and diarrhea may occur, so gastrointestinal symptoms should be carefully observed. Liver dysfunction or hepatitis symptoms may appear, and neurological adverse reactions such as seizures or cerebrovascular disorders have also been reported. Musculoskeletal adverse symptoms such as myalgia, muscle spasms, and rhabdomyolysis may occur, so muscle condition should be closely monitored. This medicine may affect driving ability or operating machinery; therefore, caution is necessary, especially at the start of treatment or when increasing the dosage. When combined with other medications, this medicine may affect metabolism or heart rhythm, so it is essential to inform healthcare providers about all medications being taken. During pregnancy, its safety has not been established, so it should not be used unless absolutely necessary, and breastfeeding women should either discontinue breastfeeding or avoid using this medicine. Safety in pediatric patients has not been established, so it is not administered to children. In case of an overdose, severe symptoms such as nausea, vomiting, bradycardia, hypotension, or respiratory depression may occur, necessitating immediate medical attention; atropine may be used as an antidote. This medicine should be taken as an orally disintegrating tablet by placing it on the tongue, allowing it to dissolve, and then swallowed with saliva or water, as it is not absorbed through the oral mucosa. Store this medicine in a tightly sealed container to prevent air and moisture ingress, and it is recommended to keep it at a temperature between 1°C and 30°C at room temperature. Proper storage will help maintain the effectiveness of the medicine.

Serious side effects

Syncope, bradycardia, heart block, QT interval prolongation, myocardial infarction, heart failure, peptic ulcers, perforated duodenal perforation, gastrointestinal bleeding, hepatitis, liver dysfunction, jaundice, seizures (epilepsy, convulsions, etc.), cerebral hemorrhage, cerebrovascular disorders, extrapyramidal disorders (motor dysfunction, ataxia, movement disorder, muscle dystonia, tremors, involuntary movements, gait disturbances, abnormal posture, speech disorders), neuroleptic malignant syndrome (stupor, extreme muscle rigidity,

Mild side effects

Nausea, vomiting, decreased appetite, diarrhea, dizziness, insomnia, headache, fatigue, drowsiness, anxiety, rash, itching, myalgia, urinary incontinence, dysuria, increased blood pressure, edema, dehydration, hyperlipidemia, insomnia, hostility, irritability, hallucinations, drowsiness, depression, confusion, emotional instability, personality changes, skin eczema, blood and lymphatic system disorders (petechiae, anemia, leukopenia, etc.), palpitations, pain, fever, increased sweating,

Store this medicine in a tightly sealed container to prevent air and moisture ingress, and it is recommended to keep it at a temperature between 1°C and 30°C at room temperature. This way, the effectiveness of the medicine can be well maintained.

Appearance

Yellow round orally disintegrating tablet

Package unit

30 tablets (10 tablets/alu-alu X 3 packs)