Humedics Lincomycin Hydrochloride Injection 600mg

Adult dosage

(Capsules) ○ Adults: For severe infections, administer lincomycin 500 mg (potency) orally every 8 hours; for very severe infections, administer 500 mg (potency) every 6 hours. For beta-hemolytic streptococcal infections, it is advisable to continue treatment for at least 10 days to prevent rheumatic fever or glomerulonephritis that may occur as sequelae after treatment. (Injection) 1. Intramuscular injection ○ Adults: For severe infections, inject lincomycin 300 mg (potency) intramuscularly twice daily; for very severe infections, inject 600 mg (potency) intramuscularly twice daily. 2. Intravenous injection ○ Adults: For severe infections, administer 600 ∼ 1,000 mg (potency) of this medicine per day by intravenous infusion in 2 ∼ 3 divided doses; the dose may be increased for very severe infections. The dose may be adjusted as appropriate according to age and symptoms. 3. Method of administration This medicine must be diluted before intravenous administration. Normal saline injection or 5 % dextrose injection may be used as the diluent. The dilution volume and infusion rate are as follows: Dose (mg) Diluent volume (mL) Infusion time (hr) 600 100 1 1000 100 1 2000 200 2 3000 300 3 4000 400 4

Children's dosage

(Capsules) Children (28 days and older): For severe infections, administer this medicine at 30 mg (potency)/kg body weight per day in 3 ∼ 4 divided doses. (Capsules) Children (28 days and older): For very severe infections, administer 60 mg (potency)/kg body weight per day in 3 ∼ 4 divided doses. 1. Intramuscular injection, children (28 days and older): For severe infections, inject this medicine intramuscularly at 10 mg (potency)/kg body weight per day in 1 ∼ 2 divided doses. 2. Intravenous injection, children (28 days and older): For severe infections, administer this medicine at 10 ∼ 20 mg (potency)/kg body weight per day by intravenous infusion in 2 ∼ 3 divided doses.

This medication can cause severe colitis and should only be used for severe infections that are difficult to treat with other antibiotics. Symptoms of colitis may include severe diarrhea, abdominal pain, and fever; if these symptoms occur, treatment should be discontinued immediately or observed closely. This medication should not be used for mild bacterial infections or non-bacterial upper respiratory infections. It does not penetrate well into cerebrospinal fluid, making it unsuitable for treating meningitis. Patients with a history of hypersensitivity, colitis, bacterial meningitis, or nursing mothers should not be administered this drug. Caution is required when administering to elderly patients or those with liver or kidney dysfunction, or a history of allergies. This medication may cause various side effects such as shock, gastrointestinal issues, respiratory problems, blood disorders, and skin rashes; any abnormal symptoms should be reported to medical personnel immediately. Regular blood tests and liver and kidney function tests should be conducted with long-term use. Antidiarrheals should not be used in conjunction with this medication, and allergic reactions should always be monitored closely. It should be avoided when combined with other neuromuscular blocking agents to prevent respiratory paralysis. It has interactions with macrolide antibiotics and should not be used together; caution is also needed with drugs that may interfere with absorption. It is best not to use this medication during pregnancy or in women who may become pregnant, and it is advisable not to administer it to newborns or premature infants due to safety concerns. Overdosage may lead to gastrointestinal disturbances, and appropriate measures should be taken immediately. This drug may affect specific blood test results, so this should be disclosed during testing. Surgical intervention may also be necessary during antibiotic treatment when needed, and care should be taken with pain or induration at the injection site. Keep out of reach of children and avoid transferring to other containers.

shock

This medication should be stored in a sealed container to prevent exposure to air and moisture, and the storage temperature should be maintained at room temperature between 1 and 30 degrees Celsius. Proper storage will help maintain the efficacy of the medication.

Appearance

A colorless and pale yellow solution in a colorless transparent ampoule.

Package unit

2mL x 50 ampoules