Telmisartan Plus Tablet 40/12.5 mg (Telmisartan, Hydrochlorothiazide)

Adult dose

Patients whose blood pressure is not adequately controlled with Telmisartan alone should take this medication once daily with water, regardless of meals. Before switching to this medication, it is recommended to adjust each active ingredient dose according to individual needs. When clinically appropriate, direct switching from monotherapy to this combination medication may also be considered. - The Telmisartan/Hydrochlorothiazide 40/12.5 mg combination can be administered to patients whose blood pressure is not adequately controlled with 40 mg of Telmisartan alone. - The Telmisartan/Hydrochlorothiazide 80/12.5 mg combination can be administered to patients whose blood pressure is not adequately controlled with 80 mg of Telmisartan alone. - The Telmisartan/Hydrochlorothiazide 80/25 mg combination can be administered to patients whose blood pressure is not adequately controlled with either the single agent 80 mg of Telmisartan or the single agent 12.5 mg of Hydrochlorothiazide. Sodium depletion or volume depletion must be corrected before starting this medication. In patients with renal impairment, No dose adjustment is needed for patients with mild to moderate renal impairment. This medication should not be given to patients with severe renal impairment (Creatinine clearance <30 mL/min). Regular monitoring of renal function is recommended. In patients with hepatic impairment, This medication should be administered with caution in patients with mild to moderate hepatic impairment. The daily dosage should not exceed 40/12.5 mg. It should not be given to patients with severe hepatic impairment (refer to precautions 2). Thiazide diuretics should be used with caution in patients with hepatic dysfunction. In the elderly, No dose modification is required. In pediatric patients, Safety and efficacy of this medication have not been established in children under 18 years of age.

Child dose

Safety and efficacy of this medication have not been established in children under 18 years of age.

This medication should not be used during pregnancy, particularly in the second and third trimesters, as it can cause serious harm to the fetus. It should not be administered to pregnant or breastfeeding women, and treatment should be discontinued immediately if pregnancy is confirmed. It should not be given to patients with an allergy to any ingredients in this medication or those with severely impaired liver or kidney function. Elderly patients, those with high potassium levels, or those with poor liver function should exercise caution while using this medication. Due to the increased risk of skin cancer, excessive sun exposure should be avoided, and immediate consultation with a physician is advisable if there are any skin abnormalities. During the course of this treatment, side effects such as dizziness, hypotension, and electrolyte imbalances may occur, and if symptoms arise, they should be reported immediately. When taken with other antihypertensives or diuretics, periodic monitoring of blood pressure, kidney function, and electrolyte levels is required. This medication may cause drowsiness or dizziness when driving or operating machinery, so caution is needed. In cases of overdose, symptoms such as hypotension, electrolyte abnormalities, and muscle cramps may occur, necessitating immediate medical attention. It is not recommended for children or adolescents under 18, as safety has not been established.

Serious side effects

Urticaria, severe swelling (edema), angioedema (including potentially fatal outcomes), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, cough with fever accompanied respiratory distress, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, loss of consciousness

Mild side effects

• Bronchitis
• pharyngitis
• sinusitis
• hypokalemia
• hyperuricemia
• hyponatremia
• anxiety
• depression
• insomnia
• sleep disturbances

This medication should be stored in a tightly sealed container to prevent air or moisture from entering. It is advisable to maintain the storage temperature between 1 and 30 degrees Celsius.

Appearance

Oval-shaped tablet composed of two layers, white and pink, with possible pink specks in the white layer.

Package unit

30 tablets/box (10 tablets/Alu-Alu X 3)