Krelova Tablets 10 mg (Rosuvastatin Calcium)

Adult dose

Administer 5 mg once daily starting at any time of the day regardless of meals. If a greater reduction in LDL cholesterol is required, the maintenance dose can be adjusted to 10 mg once daily, and the dosage can be increased up to 20 mg per day, based on patient response, with intervals of at least 4 weeks between adjustments.

Child dose

For pediatric patients aged 10 to 17 years with heterozygous familial hypercholesterolemia, a dose of 5 mg to 20 mg is administered once daily. The dose should be individually adjusted according to treatment goals, with intervals of at least 4 weeks between adjustments.

This medication should not be administered to certain patients. For example, individuals who are allergic to any component of this drug, those with severely impaired liver function, muscle disorders, or those with severely reduced kidney function, should not take this medication. Additionally, pregnant or nursing women, as well as women who could become pregnant, must consult a physician before taking this medication. This drug can affect liver function, and caution is needed for those with a history of liver disease or those who consume alcohol in excess. It is advisable to regularly check liver enzyme levels and muscle health during treatment. If symptoms such as muscle pain or weakness occur, inform your physician immediately, and treatment may be discontinued in severe cases. This drug may interact with certain medications, so it is essential to inform healthcare professionals if other medications are being taken. Particularly caution is required when taken with drugs that could increase the risk of muscle-related side effects. Pregnant or nursing women should refrain from using this medication, and women planning to become pregnant should use appropriate contraception. In cases of overdose, there is no specific antidote available; immediate medical treatment is required, with monitoring of liver function and muscle enzyme levels. Caution should also be exercised when driving or operating machinery, as dizziness may occur. Lastly, this drug contains lactose, so individuals with lactose intolerance should not use it, and dosage adjustment may be necessary for individuals of Asian descent.

Serious side effects

• Allergic reactions including urticaria and angioedema
• Severe swelling (edema)
• Chest tightness, difficulty breathing, dyspnea
• Stevens-Johnson syndrome
• Drug reaction with eosinophilia and systemic symptoms (DRESS)
• Jaundice, hepatitis
• Severe liver failure
• Severe muscle weakness, ocular muscle weakness
• Immune-mediated necrotizing myopathy
• Acute renal failure

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• fatigue
• cough

This medication must be stored in a tightly sealed container to protect it from air and moisture. It is important to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

Pink round film-coated tablets

Package unit

30 tablets (10 tablets/PTP*3)