Klerosh 10 mg (Rosuvastatin Calcium)

Adult dose

It can be taken at any time of the day, regardless of meals. The initial dose is 5 mg once daily, and the maintenance dose can be adjusted as necessary for greater LDL cholesterol reduction. The maintenance dose is 10 mg once daily for most patients. The maintenance dose may be adjusted at intervals of 4 weeks or more according to LDL cholesterol levels, treatment goals, and patient response.

Child dose

The usual dose range is 5 mg to 20 mg once daily. The dosing should be adjusted individually according to the recommended treatment goals for each patient. The dosage should be adjusted at intervals of 4 weeks or more.

This medication should not be used in certain patients. For example, those who are allergic to this medication, have severe liver disease, have muscle disorders, or have severely impaired kidney function may be at risk if they take this medication. Pregnant or nursing women, or fertile women not using proper contraception should also not take this medication. High-dose use is particularly prohibited in patients at high risk for muscle disorders. Additionally, this medication contains lactose and should not be administered to patients with lactose intolerance or related genetic conditions. It is important to periodically check liver function and muscle condition while taking this medication. Patients who consume large amounts of alcohol or have a history of liver disease require caution, and those with conditions like hypothyroidism or nephrotic syndrome must treat those conditions first. If symptoms such as myalgia, muscle weakness, or cramps appear, medical personnel must be informed immediately, and this medication may need to be discontinued if necessary. This medication may interact with other drugs, so patients should inform their doctor or pharmacist of any other medications they are taking. In particular, concurrent use with ciclosporin, fibrate drugs, or certain antibiotics and antifungals may increase the risk of muscle injury. Pregnant or nursing women should not use this medication, and fertile women must ensure proper contraception. There are no specific antidotes for overdose, so monitoring should be conducted through symptomatic treatment and tests for liver function and muscle enzymes. Lastly, this medication may cause dizziness, so caution is advised when driving or operating machinery.

Serious side effects

Allergic reactions including hives and angioedema, Stevens-Johnson syndrome, eosinophilia and systemic symptoms accompanying drug reaction syndrome (DRESS), jaundice, hepatitis, severe muscle weakness, immune-mediated necrotizing myopathy, rhabdomyolysis, acute kidney failure, oliguria, thrombocytopenia, increased serum creatinine levels, shortness of breath, ophthalmoplegia

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• myalgia
• weakness
• hematuria
• diarrhea

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture and kept in a cool place below 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication for a longer period.

Appearance

Pink round film-coated tablet

Package unit

30 tablets (10 tablets/alu-alu X3)