Crelorush 5 mg (Rosuvastatin Calcium)

Adult dose

Can be taken at any time of the day regardless of meals. The initial dose is 5 mg once daily, and the maintenance dose can be adjusted up to 10 mg once daily. The maintenance dose should be appropriately adjusted every 4 weeks or more based on LDL cholesterol levels, and can be increased up to a maximum of 20 mg per day.

Child dose

For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), doses of 5 mg to 20 mg are administered once daily. The dosage is individually adjusted according to therapeutic goals.

This medication should not be administered to certain patients. For example, those with allergies to its components, severely impaired liver function, neuromuscular disease, severe kidney impairment, and women who are pregnant or breastfeeding should not use it. Moreover, women who may become pregnant should ensure that they are highly unlikely to be pregnant before taking this medication and should use appropriate contraceptive methods. Careful use is required in patients at risk of neuromuscular disorders, such as those with slight kidney impairment, hypothyroid patients, patients with a family history of neuromuscular disorders, alcoholics, or those taking certain concurrent medications, potentially requiring dose adjustments or regular monitoring. Since this medication contains lactose, patients with lactose intolerance or related genetic disorders should not take it. Regular monitoring of liver function and muscle condition is necessary while on this medication, and immediate consultation with healthcare providers is required if symptoms such as muscle pain, weakness, fatigue, or fever occur. Additionally, this medication may interact with other drugs, so patients taking other medications must inform their healthcare providers, especially when used in combination with specific antiviral agents, immunosuppressants, and fibrate-class drugs. During pregnancy or breastfeeding, this medication should not be used, and women planning to become pregnant should consult before use. In the case of overdose, as no specific antidote exists, immediate medical attention should be sought for appropriate treatment and evaluation. Caution is needed while driving or operating machinery, as dizziness may occur. Lastly, this medication may show higher plasma concentrations in Asians, leading to a need for dose adjustments.

Serious side effects

Hives, hypersensitivity reactions including angioedema (severe allergic reactions), severe swelling (edema), chest tightness, difficulty breathing, respiratory distress, asthma attacks, severe rash with high fever, blisters, skin peeling, painful mucous membranes of the mouth/eyes (severe skin reactions), jaundice, hepatitis, liver failure, severe liver abnormalities (hepatic abnormalities including jaundice), severe headache, seizures, altered consciousness, visual disturbances, paralysis (severe neurological symptoms)

Mild side effects

Headache, dizziness, constipation, nausea, abdominal pain, itching, myalgia, weakness, hematuria, diarrhea, chest pain, cough, arthralgia, fatigue, numbness, paresthesia, chest discomfort, loss of appetite, abdominal distension, abnormal liver function tests, syncope, generalized pain, muscle cramps, gout, erectile dysfunction, depression, sleep disturbances (including insomnia and nightmares), sexual dysfunction, gynecomastia, cognitive impairment (memory loss, forgetfulness, amnesia, memory disturbance)

This medication should be stored in a tightly closed container as it may be sensitive to air and moisture. Additionally, it is important to keep it in a cool place at or below 30 degrees Celsius to maintain its efficacy.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets (10 tablets/alu-alu X 3)