Shusta Tablet 5mg (Rosuvastatin Calcium)

Adult dose

The initial dose is 5 mg once daily, and if greater reduction in LDL cholesterol is needed, the maintenance dose can be adjusted. The maintenance dose is typically 10 mg once daily, and most patients are managed at this dose. The maintenance dose should be appropriately adjusted based on LDL cholesterol levels, treatment goals, and patient response, at intervals of 4 weeks or more, and can be increased to a maximum of 20 mg once daily.

Child dose

The usual dose range for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) is 5 mg to 20 mg once daily. The dosing should be individually adjusted according to the recommended treatment goals for each patient.

This medication should not be used in certain patients. For example, patients who are allergic to any ingredient of this medication, those with severe liver function impairment, patients with myopathy, those taking certain medications concurrently, patients with severe renal impairment, and women who are pregnant or breastfeeding should not take this medication. Additionally, women who may become pregnant can only take this medication if they are unlikely to become pregnant and fully understand the risks it poses to the fetus. High-dose administration is prohibited in patients who are at high risk for myopathy, and risk factors for this include moderate renal impairment, hypothyroidism, a family history or genetic muscle disease, and alcohol dependence. This medication contains lactose, so patients with lactose intolerance or related genetic disorders should not take it. Patients with a history of liver disease or those who consume alcohol in excess need to have regular liver function tests. If symptoms of muscle pain or muscle weakness occur, the doctor should be notified immediately, and in severe cases, the medication should be discontinued. This medication may interact with some drugs, so if other medications are being taken, it is essential to consult a healthcare professional. Pregnant or breastfeeding women should not take this medication, and women who may become pregnant should ensure to use appropriate contraceptive methods. In case of overdose, there is no specific antidote, so treatment based on symptoms and tests for liver function and muscle enzymes may be required. Driving or operating machinery may cause dizziness, so caution is warranted. This medication can rarely cause serious skin reactions, liver damage, or muscle rupture; therefore, if adverse symptoms occur, immediate consultation with healthcare providers is required.

Serious side effects

Allergic reactions including urticaria, angioedema, chest discomfort, difficulty breathing, dyspnea, jaundice, hepatitis, increased transaminases, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), immune-mediated necrotizing myopathy, rhabdomyolysis, acute renal failure, oliguria, thrombocytopenia, severe muscle weakness, ocular muscle weakness, severe swelling, severe allergic reactions, severe skin reactions

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• muscle pain
• weakness
• hematuria
• diarrhea

This medication may be sensitive to air and moisture; therefore, it should be stored in a tightly closed container. Additionally, it should be kept in a cool place at or below 30 degrees Celsius to maintain its efficacy.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/box [(10 tablets/Alu-Alu × 3)]