Crovatin Tablet 10mg (Rosuvastatin Calcium)

Adult dose

Patients with primary hypercholesterolemia and related conditions should take an initial dose of 5 milligrams once daily at any time of the day, regardless of meals. If greater reduction of LDL cholesterol is needed, the maintenance dose can be adjusted to 10 milligrams once daily, and adjustments should be made according to treatment goals at intervals of 4 weeks or more. The dose may be increased up to a maximum of 20 milligrams per day.

Child dose

For pediatric patients with familial heterozygous hypercholesterolemia (ages 10 to 17), the recommended dose is 5 to 20 milligrams once daily. The dose should be adjusted individually based on treatment goals at intervals of 4 weeks or more.

This medication should not be used in certain patients. For example, it should not be administered to patients who are allergic to its components, patients with severely impaired liver function, patients with muscle disorders, patients taking certain medications, patients with severe renal impairment, or women who are pregnant or breastfeeding. Additionally, this medication should be used with caution in patients at high risk for muscle-related side effects. These patients include those with moderate to severe renal impairment, hypothyroidism, a family history of muscle disorders, patients with alcohol addiction, and the elderly. As this medication can affect liver function, patients with a history of liver disease or excessive alcohol consumption should undergo regular liver function tests before and during treatment. If symptoms such as muscle pain, muscle weakness, or cramps occur, patients should notify their doctor immediately, and a blood test should be performed to check for muscle damage. If significant muscle damage is present, the medication should be discontinued. This medication contains lactose, so patients with lactose intolerance or related genetic disorders should avoid it. This medication can interact with other medications, so patients must inform their healthcare provider about any other medications they are taking. Caution is needed when combining it with specific antivirals, immunosuppressants, antifungals, and fibrate-class drugs. Women who are pregnant or may become pregnant should use appropriate contraception and should discontinue use immediately if they become pregnant. It is also advisable for breastfeeding women not to use this medication. There is no specific antidote for overdose, so treatment should be based on symptoms, and liver and muscle function tests are necessary. Patients should be cautious as dizziness may occur while driving or operating machinery. Finally, this medication may rarely cause severe skin reactions, liver damage, renal abnormalities, or neurological symptoms in some patients, so they should consult their healthcare provider if any unusual symptoms occur.

Serious side effects

Allergic reactions including hives and angioedema, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), rhabdomyolysis, immune-mediated necrotizing myopathy, severe muscle weakness, ocular muscle weakness, cough, shortness of breath, jaundice, hepatitis, severe allergic reactions, serious skin reactions, severe neurological symptoms, severe edema or urinary abnormalities, thrombocytopenia, polyneuropathy

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• muscle pain
• weakness
• increased blood sugar
• diarrhea

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture, preferably at room temperature between 1 to 30 degrees Celsius. Storing it this way can help maintain the medication's effectiveness for a longer period.

Appearance

Pink round film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu X 2), 30 tablets/bottle