Croujez 10mg (Rosuvastatin Calcium)

Adult dose

Administer once daily at any time of the day at a starting dose of 5 milligrams, regardless of meals. If necessary, adjust the dose at intervals of 4 weeks or more to maintain a dose of 10 milligrams once daily, with a maximum dose of 20 milligrams per day if needed.

Child dose

For pediatric patients aged 10 to 17, the recommended dose is between 5 milligrams to 20 milligrams once daily. The dose may be adjusted at intervals of 4 weeks or more according to the individual patient's treatment goals.

This drug should not be used in patients with certain allergic reactions. It should not be administered to patients with active liver disease or severe liver function impairment. Patients with muscle-related disorders or muscle damage should not take this medication. It should be avoided in cases where it is taken with cyclosporine due to potential risks. This drug should not be used in patients with significantly impaired kidney function. Women who are pregnant or breastfeeding should not use this medication, and women of childbearing age should only use it when they are highly unlikely to become pregnant. Patients at high risk for muscle damage should particularly avoid high doses, and caution should be exercised in patients with risk factors such as kidney impairment, hypothyroidism, or family history. This medication contains lactose, so it is not suitable for patients with genetic issues such as lactose intolerance. Regular liver function tests and muscle-related tests should be performed during treatment, and if muscle pain or weakness occurs, medical attention should be sought immediately. If symptoms of myalgia or myopathy are severe, discontinue use and consult a physician. This medication may interact with some drugs, so it is essential to inform healthcare providers if other medications are being taken. Particular caution is necessary when used in combination with fibrate-class drugs due to increased risk of muscle damage. This medication may cause rare side effects such as interstitial lung disease or severe skin reactions, so contact healthcare personnel immediately if symptoms such as dyspnea, rash, or fever occur. Pregnant women should not take this medication, and women planning pregnancy should use appropriate contraception. In case of overdose, there is no specific antidote, and treatment should be symptom-based while monitoring liver function and muscle enzyme levels. Dizziness may occur when driving or operating machinery, so caution is advised. This medication may show higher systemic concentrations in Asians, so dose adjustments may be necessary. Blood sugar levels may rise during treatment, so patients at risk for diabetes should manage blood sugar levels thoroughly.

Serious side effects

Hypersensitivity reactions including urticaria, angioedema, chest tightness, difficulty breathing, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, severe skin reactions, severe allergic reactions, severe edema, thrombocytopenia, acute kidney failure, oliguria, severe muscle weakness, ocular myasthenia, rhabdomyolysis, immune-mediated necrotizing myopathy, serious liver damage, hyperbilirubinemia.

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• muscle pain
• weakness
• itching
• rash
• hematuria

This medication should be stored in an airtight container to avoid exposure to air or moisture, and it is best to keep it at room temperature between 1 to 30 degrees Celsius. Doing this will help maintain the drug's effectiveness and ensure safe use.

Appearance

Pink, round film-coated tablets

Package unit

For domestic use: 28 tablets (14 tablets/PTP x 2), for export: 28 tablets (14 tablets/PTP x 2)