Medication info
Dezartan Plus Tablet 16/12.5 mg

Dezartan Plus Tablet 16/12.5 mg

Prescription medicationTablet경구
Ingredient · strength
Candesartan Cilexetil›16mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
한미약품(주)
Appearance
Light orange rectangular tablet with a score line on one side
Packaging
1 bottle/box [30 tablets/bottle]
Approval status
Active

MFDS item code 200906926 · Notified 2009.09.15 · Insurance code 643505380

Summary

Main use
Improvement of essential hypertension
Who takes it
Adults
Adult dose
The recommended dosage for adults is one tablet once daily, to be taken regardless of meals. For adults, the dosage of Candesartan Cilexetil should be adjusted before switching to monotherapy with this medication. The antihypertensive effect is typically seen within 4 weeks after starting the treatment. No separate dosage adjustment is needed for elderly patients. Patients with renal impairment or liver impairment should begin with an adjusted dose of Candesartan Cilexetil. For patients with severe renal impairment or severe liver impairment, doses should be avoided.

Ingredients

Manufacturer
한미약품(주)

Efficacy & effects

Improvement of essential hypertension

  • Essential hypertension
View approved original text

This medication is used for patients with essential hypertension who have not achieved sufficient effect with individual component therapy. It effectively lowers blood pressure, thereby reducing the burden on the blood vessels and heart. This helps to decrease the risk of complications such as heart disease or stroke. More stable and sustained effects on blood pressure control can be anticipated. It is used for the treatment of essential hypertension.

How to take

Adult dose

The recommended dosage for adults is one tablet once daily, to be taken regardless of meals. For adults, the dosage of Candesartan Cilexetil should be adjusted before switching to monotherapy with this medication. The antihypertensive effect is typically seen within 4 weeks after starting the treatment. No separate dosage adjustment is needed for elderly patients. Patients with renal impairment or liver impairment should begin with an adjusted dose of Candesartan Cilexetil. For patients with severe renal impairment or severe liver impairment, doses should be avoided.

Precautions

This medication may cause serious harm or even death to the fetus and newborn during pregnancy, particularly in the second and third trimesters. Therefore, it must be discontinued immediately upon confirmation of pregnancy. Patients allergic to any component of this drug or sulfonamides, those with acute or severe kidney and liver diseases, or certain blood disorders or electrolyte imbalances should not use it. Patients with reduced blood volume or sensitivity to electrolyte imbalance, patients with heart valve disease, and those with hyperkalemia should use this medication with caution, as there is also a potential increased risk of skin cancer; it is important to limit sun exposure and regularly check skin condition. This medication may cause side effects such as headache, dizziness, fatigue, and dyspepsia, and in rare cases, abnormalities in blood, kidney, liver function, or allergic reactions may occur; if any abnormal symptoms appear, consult a healthcare professional immediately. Regular monitoring of blood pressure, kidney function, electrolyte levels, etc., is important during the use of this medication. If taken with other antihypertensives or diuretics or potassium supplements, the risk of side effects may increase due to interactions, so it is essential to consult a doctor or pharmacist. Women who are pregnant or breastfeeding should not take this medication, and breastfeeding should be discontinued during the treatment. The safety of this medication has not been confirmed in children or adolescents under 18 years old; therefore, it is advisable not to use it. Elderly individuals should take caution as excessive lowering of blood pressure may burden the heart or kidneys. In case of overdose, symptoms may include lowering of blood pressure, dizziness, electrolyte imbalance, etc.; seek immediate medical attention for appropriate treatment. This medication should be kept out of reach of children and stored in its original container to maintain the quality of the drug. Caution is advised when driving or operating machinery as dizziness or fatigue may occur.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling, angioedema, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough and fever, jaundice, extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis.

Mild side effects

  • Headache
  • back pain
  • dizziness
  • respiratory tract infections
  • symptoms similar to influenza
  • sinusitis
  • bronchitis
  • urinary tract infections
  • nausea
  • bruising
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  • tachycardia
  • fatigue
  • abdominal pain
  • pharyngitis
  • dyslipidemia
  • nasopharyngitis
  • cough
  • elevated potassium
  • creatinine
  • uric acid
  • ALT (SGPT)
  • decreased hemoglobin
  • increased AST (SGOT)
  • leukopenia
  • neutropenia
  • agranulocytosis
  • vertigo
  • intestinal vascular edema
  • diarrhea
  • liver enzyme levels.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, and it is advisable to keep it in a cool place below 30 degrees Celsius. This is to maintain the drug's effectiveness and prevent degradation.

Appearance and packaging

Appearance

Light orange rectangular tablet with a score line on one side

Package unit

1 bottle/box [30 tablets/bottle]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.