SmofKabiven Peripheral

Adult administration

The dosage and infusion rate are determined by the patient's fat removal capacity, nitrogen and carbohydrate metabolism ability, and nutritional requirements. The dosage should be individualized considering the patient's condition, weight, nutritional and energy requirements and any additional oral/enteral intakes. For children aged 12 years and above and adults: - For patients in a normal nutritional state or experiencing mild metabolic stress: 0.6-0.9 g/kg per day as amino acids (0.10

Child administration

Children aged 2-11 years: The dosage is administered regularly according to the needed amount, up to 40 mL/kg per day. The administration rate should not exceed 3.0 mL/kg per hour (equivalent to amino acids 0.10 g/kg, glucose 0.21

This medication must be used under a doctor's guidance and should not be taken arbitrarily based on self-judgment. If symptoms of anaphylactic reactions such as fever, chills, rash, or respiratory distress occur during use, administration should be immediately discontinued and medical advice sought. When administered with intravenous infusion solutions containing calcium, precipitation may occur; thus, care must be taken not to use the same infusion equipment. Particularly, in the case of premature or low birth weight infants, the metabolism of lipids may not be smooth, making the use of this medication potentially risky, requiring careful judgement. Patients with allergies to fish, eggs, soybeans, peanuts, or severe problems related to the liver, kidneys, or blood coagulation should not use this medication. Patients with certain conditions such as renal failure, diabetes, or liver dysfunction require additional caution when administering this medication, and their condition must be closely monitored. During administration, blood lipid levels and liver enzyme levels should be regularly monitored to detect adverse reactions early, and the dosage should be adjusted or discontinued if necessary. In case of overdose, symptoms such as nausea, vomiting, chills, and hyperglycemia may occur; if these symptoms arise, medical personnel should be informed immediately. This medication contains soybean oil, fish oil, and egg yolk lipids which could occasionally cause allergic reactions; therefore, caution is necessary. For pregnant or breastfeeding women, the safety of this medication has not been established, hence it should only be administered when the benefits outweigh the risks. During administration, maintaining asterile conditions is crucial to minimize infection risk, and the condition of the administration site should be frequently checked to prevent thrombosis or inflammation. Long-term use of this medication may necessitate management of trace element balance in nutritional status, and regular monitoring of blood sugar and electrolyte status is warranted. If packaging is damaged or the contents appear turbid or separated, do not use, and any unused solution should be discarded immediately after mixing. This medication should be stored in a tightly sealed container to avoid exposure to air, kept in a cool place below 25 degrees Celsius. Additionally, precautions should be taken to prevent the medication from freezing.

Serious side effects

• Urticaria
• severe swelling (edema)
• breathing difficulties
• skin rash
• anaphylactic reactions
• cyanosis
• pallor
• severe rash with high fever
• blisters
• skin peeling

Mild side effects

Loss of appetite, nausea, vomiting, increased plasma liver enzyme levels, thrombophlebitis, hypotension, hypertension, mild increase in body temperature, chills, headache, dizziness, skin rash, urticaria, flushing, headache, warmth, coldness, pallor, pain (in the throat, back, bones, chest, waist), constipation, diarrhea, stomatitis, delirium, dyspepsia, abdominal pain, hypoalbuminemia, febrile neutropenia, general weakness, edema, urinary disturbances, hematuria, weight changes

This medication should be stored in a tightly sealed container to avoid contact with air and kept in a cool place below 25 degrees Celsius. Additionally, care must be taken to prevent the medication from freezing.

Appearance

This medication consists of a plastic material container divided into three compartments, with an oxygen absorber placed between them. Each inner compartment contains an amino acid and electrolyte solution.

Package unit

1206 mL/bag [(A solution 380 mL, B solution 656 mL, C solution 170 mL) x 4], 1448 mL/bag [(A solution 456 mL, B solution 788 mL, C solution 204 mL) x 4], 1904 mL/bag [(A solution 600 mL, B solution 1036 mL, C solution 268 mL) x 4]