Tetraspan Injection 6%

Adult dosage

Administer via intravenous drip infusion, slowly administering an initial 10–20 mL while closely monitoring the patient. The daily dose and rate of administration depend on the patient's blood loss, maintenance or restoration of hemodynamic parameters, and hemodilution, which can be repeated over several days based on the patient's condition, with the duration determined by the persistence and degree of blood volume reduction, hemodynamic effects, and hemodilution. Notably, the maximum daily dose is

This medication may increase the risk of mortality, kidney damage, and excessive bleeding, and should only be used when other treatment options are not appropriate. It should not be used in patients with sepsis, kidney damage, or serious conditions. When administering this medication to patients with hypovolemia, careful evaluation of the risk of kidney damage or liver dysfunction should be undertaken, and if possible, alternative fluids should be prioritized. Calcium-containing intravenous preparations should not be administered simultaneously using the same infusion apparatus due to the potential for precipitation; infusion lines must be thoroughly cleaned if used. It should not be given to patients with specific conditions such as sepsis, severe liver disease, fluid overload, renal failure, heart failure, blood coagulation disorders, dehydration, receiving dialysis, intracranial hemorrhage, severe hypernatremia or hyperchloremia, or to patients allergic to this medication's components. Care must be taken with newborns, especially as there are risks associated with concomitant use of calcium-containing products. Dose adjustment and careful administration are necessary for patients with a history of liver disease, blood coagulation disorders, severe dehydration, and impaired kidney or liver function. During the administration of this medication, allergic reactions may occur, and patients should be closely monitored; if any abnormal symptoms arise, administration should be stopped immediately and emergency care sought. In addition, this medication may affect blood coagulation and may result in side effects such as vomiting, chills, fever, and headache. In cases of overdose, circulatory burden may occur, so dosage should be adjusted in heart failure patients, and electrolyte and fluid status as well as kidney function should be monitored regularly during administration. This medication should not be mixed with other drugs, and unused contents should be discarded immediately after opening. During pregnancy, the risks to the fetus and treatment efficacy should be considered carefully, and caution is advised during breastfeeding due to insufficient safety data. This medication can interfere with the diagnosis of pancreatitis in blood tests, so careful attention is required in interpreting test results. Overdose can lead to circulatory overload, such as pulmonary edema, and if these symptoms arise, administration should be stopped and appropriate treatment should be received. Finally, this medication should only be used for intravenous injection, kept out of reach of children, stored below 25 degrees Celsius, and not frozen.

Serious side effects

Rarely, may cause anaphylactic reactions (including hives and severe swelling), pulmonary edema, fluid overload, blood coagulation disorders, kidney damage, liver damage, pulmonary edema due to circulatory overload, severe allergic reactions, respiratory issues, severe swelling or urination abnormalities.

Mild side effects

• Rarely
• may cause vomiting
• chills
• fever
• headache
• itching
• rash
• elevated serum α-amylase levels
• tachycardia
• bradycardia

This medication should be stored in a sealed container and kept at room temperature between 1 degree and 30 degrees Celsius, ensuring that it does not freeze. Thus, it is important to avoid excessively cold or hot places and to maintain an appropriate temperature.

Appearance

A colorless to pale yellow transparent solution in a colorless transparent polyethylene container or colorless transparent plastic bag (Nexcel Pharmaceutical Film M312) used for injection.

Package unit

Bag - 500 milliliters/bag